Alcoholic liver disease natural history, complications and prognosis: Difference between revisions
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(Created page with "__NOTOC__ {{Alcoholic liver disease}} {{CMG}} ==Overview== ==Natural history, Complications and Prognosis== ===Complications=== ====Alcoholic hepatitis==== * Portal hypertensi...") |
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====Cirrhosis==== | ====Cirrhosis==== | ||
* Hepatocellular carcinoma | * Hepatocellular carcinoma | ||
* [[Hepatic encephalopathy]] | |||
===Prognosis=== | ===Prognosis=== | ||
In absence of steroid therapy 1 in every three patient dies. | In absence of steroid therapy 1 in every three patient dies. |
Revision as of 18:38, 28 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural history, Complications and Prognosis
Complications
Alcoholic hepatitis
- Portal hypertension (ascites, variceal bleeding, hepatorenal syndrome)
- Coagulopathy
- Intractable jaundice
Cirrhosis
- Hepatocellular carcinoma
- Hepatic encephalopathy
Prognosis
In absence of steroid therapy 1 in every three patient dies.
Poor Prognostic factors
- Prolonged prothrombin time
- Serum Bilirubin >10 mg/dL
- Hepatic encephalopathy
- Azotemia
- Leukocytosis
- Unresponsive to steroid treatment
- Reversal portal flow on doppler USG
Prognostic scores
- MELD score for cirrhosis
- Glasgow alcoholic hepatitis score (age, white blood cell, blood urea nitrogen, prothrombin time ratio, and bilirubin level)
- ABIC score - age, serum bilirubin, serum creatinine