Alcoholic liver disease historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]

Overview

Historical Perspective

  • Alcohol has existed as the most abused substance for many centuries[1]
  • In 1960 alcohol was recognized as a hepatotoxin
  • The earliest lesion reported for alcoholic liver disease is alcoholic steatosis (fatty liver)


References

  1. Rubin E, Lieber CS (1975). "Relation of alcoholic liver injury to cirrhosis". Clin Gastroenterol. 4 (2): 247–72. PMID 47793.

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