Adult T-cell leukemia physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]

Overview

Patients with adult T-cell leukemia usually appear lethargic and fatigued. Physical examination of patients with adult T-cell leukemia is usually remarkable for maculopapular rash, skin ulceration, and splenomegaly.

Physical Examination

The following physical findings may be observed in patients suffering from adult T-cell leukemia:^[1]^[2]^[3]^[4]

General Appearance

Adult T-cell leukemia patients often appear lethargic and fatigued.

Vital Signs

Low grade fever

Skin

Maculopapular rash
Skin ulceration
Leukemia cutis (infiltration of skin by leukemic cells)

HEENT

HEENT examination of patients with adult T-cell leukemia is usually normal.

Neck

Lymphadenopathy

Lungs

Pulmonary examination of patients with adult T-cell leukemia is usually normal.

Heart

Tachycardia
Abnormal heart rhythm may be present

Abdomen

Back

Back examination of patients with adult T-cell leukemia is usually normal.

Genitourinary

Genitourinary examination of patients with adult T-cell leukemia is usually normal.

Neuromuscular

Muscle wasting

Extremities

Muscle wasting

References

↑ Matutes E (2007). "Adult T-cell leukaemia/lymphoma". J Clin Pathol. 60 (12): 1373–7. doi:10.1136/jcp.2007.052456. PMC 2095573. PMID 18042693.CS1 maint: PMC format (link)
↑ Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J (November 2008). "Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis". World J. Gastroenterol. 14 (42): 6584–8. PMC 2773353. PMID 19030219.
↑ Taniguchi, Atsuo; Takenaka, Yoshitaka; Noda, Yumiko; Ueno, Yukio; Shichikawa, Kanji; Sato, Kazuto; Miyasaka, Nobuyuki; Nishioka, Kusuki (1988). "Adult t cell leukemia presenting with prolifeerative synovitis". Arthritis & Rheumatism. 31 (8): 1076–1077. doi:10.1002/art.1780310824. ISSN 0004-3591.
↑ Hermine, Olivier; Bouscary, Didier; Gessain, Antoine; Turlure, Pascal; Leblond, Veronique; Franck, Nathalie; Buzyn-Veil, Agnes; Rio, Bernard; Macintyre, Elisabeth; Dreyfus, Francois; Bazarbachi, Ali (1995). "Treatment of Adult T-Cell Leukemia-Lymphoma with Zidovudine and Interferon Alfa". New England Journal of Medicine. 332 (26): 1749–1751. doi:10.1056/NEJM199506293322604. ISSN 0028-4793.

[pmid18042693-1] Matutes E (2007). "Adult T-cell leukaemia/lymphoma". J Clin Pathol. 60 (12): 1373–7. doi:10.1136/jcp.2007.052456. PMC 2095573. PMID 18042693.CS1 maint: PMC format (link)

[pmid19030219-2] Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J (November 2008). "Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis". World J. Gastroenterol. 14 (42): 6584–8. PMC 2773353. PMID 19030219.

[TaniguchiTakenaka1988-3] Taniguchi, Atsuo; Takenaka, Yoshitaka; Noda, Yumiko; Ueno, Yukio; Shichikawa, Kanji; Sato, Kazuto; Miyasaka, Nobuyuki; Nishioka, Kusuki (1988). "Adult t cell leukemia presenting with prolifeerative synovitis". Arthritis & Rheumatism. 31 (8): 1076–1077. doi:10.1002/art.1780310824. ISSN 0004-3591.

[HermineBouscary1995-4] Hermine, Olivier; Bouscary, Didier; Gessain, Antoine; Turlure, Pascal; Leblond, Veronique; Franck, Nathalie; Buzyn-Veil, Agnes; Rio, Bernard; Macintyre, Elisabeth; Dreyfus, Francois; Bazarbachi, Ali (1995). "Treatment of Adult T-Cell Leukemia-Lymphoma with Zidovudine and Interferon Alfa". New England Journal of Medicine. 332 (26): 1749–1751. doi:10.1056/NEJM199506293322604. ISSN 0028-4793.

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