Adult-onset Still's disease historical perspective: Difference between revisions

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* In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.<ref name="urlWhat is Still’s Disease? | Stills Disease Information Center">{{cite web |url=http://www.stillsdisease.org/index.php/stills-info/ |title=What is Still’s Disease? &#124; Still's Disease Information Center |format= |work= |accessdate=}}</ref>
* In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.<ref name="urlWhat is Still’s Disease? | Stills Disease Information Center">{{cite web |url=http://www.stillsdisease.org/index.php/stills-info/ |title=What is Still’s Disease? &#124; Still's Disease Information Center |format= |work= |accessdate=}}</ref>
* Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA).
* Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA).
* In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA.
* In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA.<ref name="pmid5315135">{{cite journal |vauthors=Bywaters EG |title=Still's disease in the adult |journal=Ann. Rheum. Dis. |volume=30 |issue=2 |pages=121–33 |date=March 1971 |pmid=5315135 |pmc=1005739 |doi= |url=}}</ref>
* The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs)
* The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs)
* There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission.
* There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission.

Revision as of 22:03, 22 April 2018

Adult-onset Still's disease

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Historical Perspective

  • Adult-onset Still's disease is an inflammatory condition characterized by high spiking fevers, rash, sore throat, and joint pain.[1]
  • As it progresses, adult-onset Still's disease may lead to chronic arthritis and other complications.
  • In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.[2]
  • Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA).
  • In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA.[3]
  • The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs)
  • There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission.

References

  1. "Adult Still disease: MedlinePlus Medical Encyclopedia".
  2. "What is Still's Disease? | Still's Disease Information Center".
  3. Bywaters EG (March 1971). "Still's disease in the adult". Ann. Rheum. Dis. 30 (2): 121–33. PMC 1005739. PMID 5315135.

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