Adiposogenital dystrophy causes
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Template:Adiposogenital Dystrophy
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ogechukwu Hannah Nnabude, MD
Overview
There are various types of lesion that can lead to adiposogenital dystrophy, most of which result from an injury of a part of the arcuate nucleus and ventromedial nuclei of the hypothalamus. Deep brain stimulation has also been seen to produce similar symptoms in patients with Parkinson's disease.
Causes
- The most common cause of adiposogenital dystrophy are tumors affecting the hypothalamus or pituitary. In children, the most common tumor that would cause adiposogenital dystrophy is a craniopharyngioma, a tumor arising from the Ratke's pouch[1].
- Inflammation due to infections such as tuberculosis, and encephalitis [2] [3]
- Deep brain stimulation [6] [7]. Some patients were observed to have an increase in weight of up to 20kg[8].
- Other causes of adiposogenital dystrophy include Friedreich ataxia, demyelinating diseases, and microcephaly[15] [16]
- ↑ Babinski-fröhlich syndrome. Bissonnette B, & Luginbuehl I, & Marciniak B, & Dalens B.J.(Eds.), (2006). Syndromes: Rapid Recognition and Perioperative Implications. McGraw Hill. https://accessanesthesiology.mhmedical.com/content.aspx?bookid=852§ionid=49517244
- ↑ Aulakh R, Chopra S (2018). "Pediatric Tubercular Meningitis: A Review". J Pediatr Neurosci. 13 (4): 373–382. doi:10.4103/JPN.JPN_78_18. PMC 6413593. PMID 30937075.
- ↑ Babinski-fröhlich syndrome. Bissonnette B, & Luginbuehl I, & Marciniak B, & Dalens B.J.(Eds.), (2006). Syndromes: Rapid Recognition and Perioperative Implications. McGraw Hill. https://accessanesthesiology.mhmedical.com/content.aspx?bookid=852§ionid=49517244
- ↑ Molina A, Mañá J, Villabona C, Fernández-Castañer M, Soler J (2002). "Hypothalamic-pituitary sarcoidosis with hypopituitarism. Long-term remission with methylprednisolone pulse therapy". Pituitary. 5 (1): 33–6. doi:10.1023/a:1022153401880. PMID 12638724.
- ↑ Belojevic G, Maric-Zivkovic J (2005) Sarcoidosis and obesity. Med Pregl 58(Suppl 1):44–45 Medline
- ↑ Tuite PJ, Maxwell RE, Ikramuddin S, Kotz CM, Kotzd CM, Billington CJ; et al. (2005). "Weight and body mass index in Parkinson's disease patients after deep brain stimulation surgery". Parkinsonism Relat Disord. 11 (4): 247–52. doi:10.1016/j.parkreldis.2005.01.006. PMID 15878586.
- ↑ Romito LM, Scerrati M, Contarino MF, Iacoangeli M, Bentivoglio AR, Albanese A (2003) Bilateral high frequency subthalamic stimulation in Parkinson’s disease: long-term neurological follow-up. J Neurosurg Sci 47:119–128 Medline
- ↑ Montaurier C, Morio B, Bannier S, Derost P, Arnaud P, Brandolini-Bunlon M; et al. (2007). "Mechanisms of body weight gain in patients with Parkinson's disease after subthalamic stimulation". Brain. 130 (Pt 7): 1808–18. doi:10.1093/brain/awm113. PMID 17535833.
- ↑ van Iersel L, Li Z, Srivastava DK, Brinkman TM, Bjornard KL, Wilson CL, Green DM, Merchant TE, Pui CH, Howell RM, Smith SA, Armstrong GT, Hudson MM, Robison LL, Ness KK, Gajjar A, Krull KR, Sklar CA, van Santen HM, Chemaitilly W. Hypothalamic-Pituitary Disorders in Childhood Cancer Survivors: Prevalence, Risk Factors and Long-Term Health Outcomes. J Clin Endocrinol Metab. 2019 Dec 01;104(12):6101-6115.
- ↑ Chemaitilly W, Armstrong GT, Gajjar A, Hudson MM. Hypothalamic-Pituitary Axis Dysfunction in Survivors of Childhood CNS Tumors: Importance of Systematic Follow-Up and Early Endocrine Consultation. J Clin Oncol. 2016 Dec 20;34(36):4315-4319.
- ↑ Krahulik D, Zapletalova J, Frysak Z, Vaverka M. Dysfunction of hypothalamic-hypophysial axis after traumatic brain injury in adults. J Neurosurg. 2010 Sep;113(3):581-4.
- ↑ Tudor RM, Thompson CJ. Posterior pituitary dysfunction following traumatic brain injury: review. Pituitary. 2019 Jun;22(3):296-304.
- ↑ Bhandare N, Kennedy L, Malyapa RS, Morris CG, Mendenhall WM. Hypopituitarism after radiotherapy for extracranial head and neck cancers. Head Neck. 2008 Sep;30(9):1182-92.
- ↑ Sfeir JG, Kittah NEN, Tamhane SU, Jasim S, Chemaitilly W, Cohen LE, Murad MH. Diagnosis of GH Deficiency as a Late Effect of Radiotherapy in Survivors of Childhood Cancers. J Clin Endocrinol Metab. 2018 Aug 01;103(8):2785-2793.
- ↑ Babinski-fröhlich syndrome. Bissonnette B, & Luginbuehl I, & Marciniak B, & Dalens B.J.(Eds.), (2006). Syndromes: Rapid Recognition and Perioperative Implications. McGraw Hill. https://accessanesthesiology.mhmedical.com/content.aspx?bookid=852§ionid=49517244
- ↑ Burfeind KG, Yadav V, Marks DL. Hypothalamic Dysfunction and Multiple Sclerosis: Implications for Fatigue and Weight Dysregulation. Curr Neurol Neurosci Rep. 2016 Nov;16(11):98.