Acute retinal necrosis

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Acute retinal necrosis
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eMedicine oph/377 
MeSH D015882

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acute retinal necrosis is a type of retinitis which can be associated with viral infections.

It was first characterized in 1971.[1][2]

One study indicated an incidence of 1 per 1.6 to 2.0 million.[3]

Causes

The exact causes are not known, but varicella zoster virus is frequently implicated,[4] and other herpesviruses can be involved.[5]

Treatment

Treatments that have been used include foscarnet,[6] valacyclovir and famciclovir.[7]

See also

References

  1. "eMedicine - Acute Retinal Necrosis : Article by Andrew A Dahl, MD". Archived from the original on 16 February 2008. Retrieved 2008-02-05.
  2. Urayama A, Yamada N, Sasaki T: Unilateral acute uveitis with retinal periarteritis and detachment. Jpn J Clin Ophthalmol 1971; 25: 607.
  3. Muthiah MN, Michaelides M, Child CS, Mitchell SM (2007). "Acute retinal necrosis: a national population‐based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK". Br J Ophthalmol. 91 (11): 1452–5. doi:10.1136/bjo.2007.114884. PMC 2095441. PMID 17504853.
  4. Lau CH, Missotten T, Salzmann J, Lightman SL (2007). "Acute retinal necrosis features, management, and outcomes". Ophthalmology. 114 (4): 756–62. doi:10.1016/j.ophtha.2006.08.037. PMID 17184841.
  5. Kezuka T, Atherton SS (2007). "Acute retinal necrosis". Chem Immunol Allergy. Chemical Immunology and Allergy. 92: 244–53. doi:10.1159/000099275. ISBN 3-8055-8187-4. PMID 17264500.
  6. King J, Chung M, DiLoreto DA (2007). "A 9 year-old girl with herpes simplex virus type 2 acute retinal necrosis treated with intravitreal foscarnet". Ocul. Immunol. Inflamm. 15 (5): 395–8. doi:10.1080/09273940701486431. PMID 17972224.
  7. Emerson GG, Smith JR, Wilson DJ, Rosenbaum JT, Flaxel CJ (2006). "Primary treatment of acute retinal necrosis with oral antiviral therapy". Ophthalmology. 113 (12): 2259–61. doi:10.1016/j.ophtha.2006.05.063. PMID 16996614.

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