Acute disseminated encephalomyelitis causes: Difference between revisions

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==Overview==
==Overview==
In the vast majority of cases, the causal pathogen is unknown. Acute disseminated encephalomyelitis is a clinical illness that can be roughly classified as encephalomyelitis with numerous inflammatory demyelination, autoimmune reasons, and a connection to a previous infection or vaccine.


==Causes==
==Causes==
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*Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating multifocal disease of the central nervous system that most commonly affects children after immunization or viral infections of respiratory or gastrointestinal tracts and carries a high risk of neurological sequelae if not treated promptly.<ref name="pmid30753808">{{cite journal| author=Alves JM, Marques IB, Gil-Gouveia R| title=[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]. | journal=Acta Med Port | year= 2019 | volume= 32 | issue= 1 | pages= 81-85 | pmid=30753808 | doi=10.20344/amp.9809 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30753808  }}</ref>
* Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating multifocal disease of the central nervous system that most commonly affects children after immunization or viral infections of respiratory or gastrointestinal tracts and carries a high risk of neurological sequelae if not treated promptly.<ref name="pmid30753808">{{cite journal| author=Alves JM, Marques IB, Gil-Gouveia R| title=[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]. | journal=Acta Med Port | year= 2019 | volume= 32 | issue= 1 | pages= 81-85 | pmid=30753808 | doi=10.20344/amp.9809 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30753808  }}</ref>
*Common causes are cytomegalovirus, Epstein-Barr virus, herpes simplex virus, human herpes-virus-6, influenza virus, hepatitis A, human immunodeficiency virus, and mycoplasma pneumonia.
 
*Common causes are cytomegalovirus, Epstein-Barr virus, herpes simplex virus, human herpes-virus-6, influenza virus, hepatitis A, human immunodeficiency virus, and mycoplasma pneumonia.<ref name="pmid30753808">{{cite journal| author=Alves JM, Marques IB, Gil-Gouveia R| title=[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]. | journal=Acta Med Port | year= 2019 | volume= 32 | issue= 1 | pages= 81-85 | pmid=30753808 | doi=10.20344/amp.9809 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30753808  }} </ref>
*The rabies vaccine was the first vaccine to be linked to acute disseminated encephalomyelitis <ref name="pmid30730236">{{cite journal| author=Rossor T, Benetou C, Wright S, Duignan S, Lascelles K, Robinson R | display-authors=etal| title=Early predictors of epilepsy and subsequent relapse in children with acute disseminated encephalomyelitis. | journal=Mult Scler | year= 2020 | volume= 26 | issue= 3 | pages= 333-342 | pmid=30730236 | doi=10.1177/1352458518823486 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30730236  }}</ref>
*The rabies vaccine was the first vaccine to be linked to acute disseminated encephalomyelitis <ref name="pmid30730236">{{cite journal| author=Rossor T, Benetou C, Wright S, Duignan S, Lascelles K, Robinson R | display-authors=etal| title=Early predictors of epilepsy and subsequent relapse in children with acute disseminated encephalomyelitis. | journal=Mult Scler | year= 2020 | volume= 26 | issue= 3 | pages= 333-342 | pmid=30730236 | doi=10.1177/1352458518823486 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30730236  }}</ref>


==References==
==References==

Revision as of 02:44, 1 November 2021

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Overview

In the vast majority of cases, the causal pathogen is unknown. Acute disseminated encephalomyelitis is a clinical illness that can be roughly classified as encephalomyelitis with numerous inflammatory demyelination, autoimmune reasons, and a connection to a previous infection or vaccine.

Causes


  • Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating multifocal disease of the central nervous system that most commonly affects children after immunization or viral infections of respiratory or gastrointestinal tracts and carries a high risk of neurological sequelae if not treated promptly.[1]
  • Common causes are cytomegalovirus, Epstein-Barr virus, herpes simplex virus, human herpes-virus-6, influenza virus, hepatitis A, human immunodeficiency virus, and mycoplasma pneumonia.[1]
  • The rabies vaccine was the first vaccine to be linked to acute disseminated encephalomyelitis [2]


References


  1. 1.0 1.1 Alves JM, Marques IB, Gil-Gouveia R (2019). "[Vaccination Controversies: An Adult Case of Post-Vaccinal Acute Disseminated Encephalomyelitis]". Acta Med Port. 32 (1): 81–85. doi:10.20344/amp.9809. PMID 30753808.
  2. Rossor T, Benetou C, Wright S, Duignan S, Lascelles K, Robinson R; et al. (2020). "Early predictors of epilepsy and subsequent relapse in children with acute disseminated encephalomyelitis". Mult Scler. 26 (3): 333–342. doi:10.1177/1352458518823486. PMID 30730236.