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*Medical evaluation for acute diarrhea is recommended for patients with [[fever]], mucoid or [[Dysentery|bloody diarrhea]], [[abdominal pain]] and symptoms of [[dehydration]](dizziness or light headedness, dark urine, [[fatigue]]).
*Medical evaluation for acute diarrhea is recommended for patients with [[fever]], mucoid or [[Dysentery|bloody diarrhea]], [[abdominal pain]] and symptoms of [[dehydration]](dizziness or light headedness, dark urine, [[fatigue]]).
*Hospital admission is required for individuals who present with acute diarrhea, if there is a medical history of [[immunosuppression]] (eg, treatment for [[Cancer|malignancy]], [[Organ transplant|transplantation]], or advanced [[HIV AIDS|HIV infection]]), with preexisting [[Intestine|bowel]] disease ([[Inflammatory bowel disease]] or [[Ischemic colitis]]) or  with significant vascular or [[Circulatory system|cardiovascular]] disease.
*Hospital admission is required for individuals who present with acute diarrhea, if there is a medical history of [[immunosuppression]] (eg, treatment for [[Cancer|malignancy]], [[Organ transplant|transplantation]], or advanced [[HIV AIDS|HIV infection]]), with preexisting [[Intestine|bowel]] disease ([[Inflammatory bowel disease]] or [[Ischemic colitis]]) or  with significant vascular or [[Circulatory system|cardiovascular]] disease.
*Symptoms of acute diarrhea include loose stools (watery, bloody or mucoid), fever, [[abdominal pain]], excessive thirst, dark or scant urine, light headedness.  
*Symptoms of acute diarrhea include loose stools (watery, bloody or mucoid), [[fever]], [[abdominal pain]], excessive thirst, dark or scant urine, [[Dizziness|light headedness]].  
===History===
===History===
*Initial evaluation of patients who present with acute diarrhea include:<ref name="pmid18666921">{{cite journal |vauthors=Greenwood Z, Black J, Weld L, O'Brien D, Leder K, Von Sonnenburg F, Pandey P, Schwartz E, Connor BA, Brown G, Freedman DO, Torresi J |title=Gastrointestinal infection among international travelers globally |journal=J Travel Med |volume=15 |issue=4 |pages=221–8 |year=2008 |pmid=18666921 |doi=10.1111/j.1708-8305.2008.00203.x |url=}}</ref><ref name="pmid16395094">{{cite journal |vauthors=Vernacchio L, Vezina RM, Mitchell AA, Lesko SM, Plaut AG, Acheson DW |title=Diarrhea in American infants and young children in the community setting: incidence, clinical presentation and microbiology |journal=Pediatr. Infect. Dis. J. |volume=25 |issue=1 |pages=2–7 |year=2006 |pmid=16395094 |doi= |url=}}</ref><ref name="pmid17357047">{{cite journal |vauthors=Fischer TK, Viboud C, Parashar U, Malek M, Steiner C, Glass R, Simonsen L |title=Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003 |journal=J. Infect. Dis. |volume=195 |issue=8 |pages=1117–25 |year=2007 |pmid=17357047 |doi=10.1086/512863 |url=}}</ref><ref name="pmid22675542">{{cite journal |vauthors=Talbert A, Thuo N, Karisa J, Chesaro C, Ohuma E, Ignas J, Berkley JA, Toromo C, Atkinson S, Maitland K |title=Diarrhoea complicating severe acute malnutrition in Kenyan children: a prospective descriptive study of risk factors and outcome |journal=PLoS ONE |volume=7 |issue=6 |pages=e38321 |year=2012 |pmid=22675542 |pmc=3366921 |doi=10.1371/journal.pone.0038321 |url=}}</ref>
*Initial evaluation of patients who present with acute diarrhea include:<ref name="pmid18666921">{{cite journal |vauthors=Greenwood Z, Black J, Weld L, O'Brien D, Leder K, Von Sonnenburg F, Pandey P, Schwartz E, Connor BA, Brown G, Freedman DO, Torresi J |title=Gastrointestinal infection among international travelers globally |journal=J Travel Med |volume=15 |issue=4 |pages=221–8 |year=2008 |pmid=18666921 |doi=10.1111/j.1708-8305.2008.00203.x |url=}}</ref><ref name="pmid16395094">{{cite journal |vauthors=Vernacchio L, Vezina RM, Mitchell AA, Lesko SM, Plaut AG, Acheson DW |title=Diarrhea in American infants and young children in the community setting: incidence, clinical presentation and microbiology |journal=Pediatr. Infect. Dis. J. |volume=25 |issue=1 |pages=2–7 |year=2006 |pmid=16395094 |doi= |url=}}</ref><ref name="pmid17357047">{{cite journal |vauthors=Fischer TK, Viboud C, Parashar U, Malek M, Steiner C, Glass R, Simonsen L |title=Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003 |journal=J. Infect. Dis. |volume=195 |issue=8 |pages=1117–25 |year=2007 |pmid=17357047 |doi=10.1086/512863 |url=}}</ref><ref name="pmid22675542">{{cite journal |vauthors=Talbert A, Thuo N, Karisa J, Chesaro C, Ohuma E, Ignas J, Berkley JA, Toromo C, Atkinson S, Maitland K |title=Diarrhoea complicating severe acute malnutrition in Kenyan children: a prospective descriptive study of risk factors and outcome |journal=PLoS ONE |volume=7 |issue=6 |pages=e38321 |year=2012 |pmid=22675542 |pmc=3366921 |doi=10.1371/journal.pone.0038321 |url=}}</ref>
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**'''Frequency and nature of stools:'''
**'''Frequency and nature of stools:'''
***It can suggest whether the diarrhea is originating in the small or the large [[Intestine|bowel]].
***It can suggest whether the diarrhea is originating in the small or the large [[Intestine|bowel]].
****Diarrhea of [[Small intestine|small bowel]] origin is typically watery, of large volume, and associated with abdominal cramping, bloating, and gas. [[Fever]] is less common and [[Human feces|stools]] are mostly watery.
****Diarrhea of [[Small intestine|small bowel]] origin is typically watery, of large volume, and associated with [[Abdominal pain|abdominal cramping]], bloating, and gas. [[Fever]] is less common and [[Human feces|stools]] are mostly watery.
****Diarrhea of [[Large intestine|large intestinal]] origin often presents with frequent, regular, small volume, and painful [[Defecation|bowel movements]]. [[Fever]] and bloody or mucoid stools are common.
****Diarrhea of [[Large intestine|large intestinal]] origin often presents with frequent, regular, small volume, and painful [[Defecation|bowel movements]]. [[Fever]] and bloody or mucoid stools are common.
**'''History of associated symptoms:''' [[Fever]], [[abdominal pain]], [[nausea and vomiting]]
**'''History of associated symptoms:''' [[Fever]], [[abdominal pain]], [[nausea and vomiting]]
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***'''Travel history:'''  
***'''Travel history:'''  
****Travel history may be helpful in identifying a cause for diarrhea.   
****Travel history may be helpful in identifying a cause for diarrhea.   
****The risk of travelers diarrhea is high in regions where hygienic practices and [[sanitation]] are poor.  
****The risk of [[traveler's diarrhea]] is high in regions where hygienic practices and [[sanitation]] are poor.  
****Traveler's diarrhea risk also varies with season of the year, higher risk during warmer months and rainy seasons.
****[[Traveler's diarrhea]] risk also varies with season of the year, higher risk during warmer months and rainy seasons.
****'''Risk by geographic regions:'''
****'''Risk by geographic regions:'''
*****High risk: South and Southeast Asia, Central and western Africa, South and Central America, and Mexico
*****High risk: South and Southeast Asia, Central and western Africa, South and Central America, and Mexico
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****[[Cryptosporidium|Cryptosporidium species]]
****[[Cryptosporidium|Cryptosporidium species]]
*'''Food history:'''  
*'''Food history:'''  
**Intake of raw or uncooked food is a common cause of infectious diarrhea. Consumption of undercooked or raw meat or fish, unpasteurized dairy products, or certain organic vitamin preperations may suggest certain pathogens.
**Intake of raw or uncooked food is a common cause of infectious diarrhea. Consumption of undercooked or raw meat or fish, unpasteurized dairy products, or certain organic vitamin preperations may suggest certain [[Pathogen|pathogens]].
***Meats: [[Clostridium perfringens|C. perfringens]], [[Aeromonas]], [[Campylobacter]], and [[Salmonella]] species
***Meats: [[Clostridium perfringens|C. perfringens]], [[Aeromonas]], [[Campylobacter]], and [[Salmonella]] species
***Dairy food: [[Campylobacter]], [[Salmonella]] species, [[Listeria monocytogenes|Listeria]] especially in pregnancy.
***Dairy food: [[Campylobacter]], [[Salmonella]] species, [[Listeria monocytogenes|Listeria]] especially in pregnancy.
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***Pork: [[Clostridium perfringens|C. perfringens]], [[Yersinia Enterocolitica Infection|Y. enterocolitica]]
***Pork: [[Clostridium perfringens|C. perfringens]], [[Yersinia Enterocolitica Infection|Y. enterocolitica]]
**Although it is often difficult to know which food exposure was the potential cause, the timing of onset of symptoms following exposure to the suspected food can be an important clue to find the diagnosis.
**Although it is often difficult to know which food exposure was the potential cause, the timing of onset of symptoms following exposure to the suspected food can be an important clue to find the diagnosis.
***Up to 6 hrs: Ingestion of a preformed toxin produced by [[Staphylococcus aureus]] or [[Bacillus cereus]], if [[Nausea and vomiting|nausea]] and [[Nausea and vomiting|vomiting]] were the initial symptoms.
***Up to 6 hrs: Ingestion of a preformed [[toxin]] produced by [[Staphylococcus aureus]] or [[Bacillus cereus]], if [[Nausea and vomiting|nausea]] and [[Nausea and vomiting|vomiting]] were the initial symptoms.
***Between 8 to 16 hours: suggests infection with [[Clostridium perfringens]]
***Between 8 to 16 hours: suggests [[infection]] with [[Clostridium perfringens]]
***After 16 hours: Most commonly either [[Virus|viral]] or other [[Bacteria|bacterial]] infection (eg, [[Pollution|contamination]] of food with [[ETEC|enterotoxigenic E.coli]], [[EHEC]] or other pathogens).
***After 16 hours: Most commonly either [[Virus|viral]] or other [[Bacteria|bacterial]] infection (eg, [[Pollution|contamination]] of food with [[ETEC|enterotoxigenic E.coli]], [[EHEC]] or other pathogens).


* '''Water exposure''':   
* '''Water exposure''':   
** Water is the main source for organisms that cause diarrhea.   
** Water is the main source for organisms that cause diarrhea.   
** Swimming pools have been associated with outbreaks of infection with [[Shigella]] species.   
** Swimming pools have been associated with outbreaks of [[infection]] with [[Shigella]] species.   
** [[Aeromonas]] infection is associated with exposure to the marine environment.   
** [[Aeromonas]] infection is associated with exposure to the marine environment.   
** Certain organisms are resistant to chlorination ([[Giardia lamblia|Giardia]], [[Cryptosporidium]], and [[Entamoeba]]), so exposure to contaminated water should raise the suspicion of [[infection]] with these [[Pathogen|pathogens]].   
** Certain organisms are resistant to chlorination ([[Giardia lamblia|Giardia]], [[Cryptosporidium]], and [[Entamoeba]]), so exposure to contaminated water should raise the suspicion of [[infection]] with these [[Pathogen|pathogens]].   
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**Poultry, petting zoos has been associated with [[Salmonella]] and [[Campylobacter]] infections.
**Poultry, petting zoos has been associated with [[Salmonella]] and [[Campylobacter]] infections.
*'''Medical history:'''
*'''Medical history:'''
**Various medical conditions can make patients prone to infections.
**Various medical conditions can make patients prone to [[Infection|infections]].
***[[Clostridium difficile infection|C. difficile]]: [[Hospital|Hospitalization]], [[antibiotic]] administration
***[[Clostridium difficile infection|C. difficile]]: [[Hospital|Hospitalization]], [[antibiotic]] administration
***[[Plesiomonas shigelloides|Plesiomonas]] species: Liver diseases or [[Cancer|malignancy]]
***[[Plesiomonas shigelloides|Plesiomonas]] species: [[Liver]] diseases or [[Cancer|malignancy]]
***[[Salmonella]] species: Intestinal dysmotility, [[malnutrition]], [[achlorhydria]], [[hemolytic anemia]] (especially [[Sickle-cell disease|sickle cell disease]]), [[immunosuppression]], [[malaria]]
***[[Salmonella]] species: [[Intestine|Intestinal]] [[Motility|dysmotility]], [[malnutrition]], [[achlorhydria]], [[hemolytic anemia]] (especially [[Sickle-cell disease|sickle cell disease]]), [[immunosuppression]], [[malaria]]
***[[Rotavirus]]: [[Hospital|Hospitalization]]
***[[Rotavirus]]: [[Hospital|Hospitalization]]
***[[Giardia lamblia|Giardia]] species: [[X-linked agammaglobulinemia|Agammaglobulinemia]], [[chronic pancreatitis]], [[achlorhydria]], [[cystic fibrosis]]
***[[Giardia lamblia|Giardia]] species: [[X-linked agammaglobulinemia|Agammaglobulinemia]], [[chronic pancreatitis]], [[achlorhydria]], [[cystic fibrosis]]
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**[[Fatigue]]
**[[Fatigue]]
===Less Common Symptoms===
===Less Common Symptoms===
Less common symptoms of Acute diarrhea include:
Less common symptoms of acute diarrhea include:
*[[Weight loss]] if diarrhea persists longer
*[[Weight loss]] if diarrhea persists longer
*[[Malnutrition]]
*[[Malnutrition]]

Revision as of 20:57, 9 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

The hallmark of acute diarrhea is the sudden onset of 3 or more stools per day, lasting less than 2 weeks. The most common symptoms of acute diarrhea include increased frequency of bowel movements, abdominal pain, elevation of body temperature, symptoms of fluid loss (dark or scant urine, excessive thirst, dizziness, fatigue).

History and Symptoms

History

  • Water exposure:
    • Water is the main source for organisms that cause diarrhea.
    • Swimming pools have been associated with outbreaks of infection with Shigella species.
    • Aeromonas infection is associated with exposure to the marine environment.
    • Certain organisms are resistant to chlorination (Giardia, Cryptosporidium, and Entamoeba), so exposure to contaminated water should raise the suspicion of infection with these pathogens.
    • Camping history with exposure to water sources may also suggest infection with Giardia.

Common Symptoms

Common symptoms of acute diarrhea include:

Less Common Symptoms

Less common symptoms of acute diarrhea include:

References

  1. Greenwood Z, Black J, Weld L, O'Brien D, Leder K, Von Sonnenburg F, Pandey P, Schwartz E, Connor BA, Brown G, Freedman DO, Torresi J (2008). "Gastrointestinal infection among international travelers globally". J Travel Med. 15 (4): 221–8. doi:10.1111/j.1708-8305.2008.00203.x. PMID 18666921.
  2. Vernacchio L, Vezina RM, Mitchell AA, Lesko SM, Plaut AG, Acheson DW (2006). "Diarrhea in American infants and young children in the community setting: incidence, clinical presentation and microbiology". Pediatr. Infect. Dis. J. 25 (1): 2–7. PMID 16395094.
  3. Fischer TK, Viboud C, Parashar U, Malek M, Steiner C, Glass R, Simonsen L (2007). "Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003". J. Infect. Dis. 195 (8): 1117–25. doi:10.1086/512863. PMID 17357047.
  4. Talbert A, Thuo N, Karisa J, Chesaro C, Ohuma E, Ignas J, Berkley JA, Toromo C, Atkinson S, Maitland K (2012). "Diarrhoea complicating severe acute malnutrition in Kenyan children: a prospective descriptive study of risk factors and outcome". PLoS ONE. 7 (6): e38321. doi:10.1371/journal.pone.0038321. PMC 3366921. PMID 22675542.

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