Acute bronchitis medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acute bronchitis may be treated through multiple pharmacologic regimens such as antibiotics and antihistamine.

Antibiotics

In most cases, acute bronchitis is caused by viruses, not bacteria and it will go away on its own without antibiotics. To treat acute bronchitis that appears to be caused by a bacterial infection, or as a precaution, antibiotics may be given.[1] However, a meta-analysis found that antibiotics may reduce symptoms by one-half day.[2]

Antihistamines

Using over-the-counter antihistamines may be harmful in the self-treatment of bronchitis.[3]

An effect of antihistamines is to thicken mucus secretions. Expelling infected mucus via coughing can be beneficial in recovering from bronchitis. Expulsion of the mucus may be hindered if it is thickened. Antihistamines can help bacteria to persist and multiply in the lungs by increasing its residence time in a warm, moist environment of thickened mucus.

Using antihistamines along with an expectorant cough syrup may be doubly harmful: encouraging the production of mucus and then thickening that which is produced. Using an expectorant cough syrup alone might be useful in flushing bacteria from the lungs. Using an antihistamine along with it works against the intention of using the expectorant.

References

  1. The Merck Manual of Medical Information: Bronchitis. February 2003. Accessed 20 March 2007.
  2. Bent S, Saint S, Vittinghoff E, Grady D (1999). "Antibiotics in acute bronchitis: a meta-analysis". Am. J. Med. 107 (1): 62–7. PMID 10403354.
  3. Merck Manual Home Edition: Symptoms and Diagnosis of Lung Disorders: Symptoms. November 2006. Accessed 6 October 2007.


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