|
|
Line 1: |
Line 1: |
| __NOTOC__
| | #Redirect [[Melanoma]] |
| {{DiseaseDisorder infobox |
| |
| Name = Acral lentiginous melanoma |
| |
| ICD10 = C43 |
| |
| ICD9 = {{ICD9|172.0}}-{{ICD9|173.9}} |
| |
| ICDO = 8744/3 |
| |
| Image = Subungual melanoma.jpg|
| |
| }}
| |
| {{SI}}
| |
| | |
| {{CMG}}
| |
| | |
| ==Overview==
| |
| '''Acral lentiginous melanoma''' is a kind of skin [[melanoma]]. It is also known as subungual melanoma. It is seen on the palms, soles and under the nails.
| |
| | |
| ==Pathophysiology==
| |
| | |
| ===Microscopic Pathology===
| |
| '''The microscopic hallmarks are:'''
| |
| * Atypical [[melanocyte]]s in junctional nests
| |
| * [[Dermis|dermal]] invasion
| |
| * [[Desmoplasia]]
| |
| * [[Hyperplastic]] [[Epidermis (skin)|epidermis]]
| |
| | |
| ==Epidemiology and Demographics==
| |
| ===Age===
| |
| The average age at diagnosis is between sixty and seventy years.
| |
| | |
| ===Race===
| |
| This is the most common form of melanoma in [[Asian people|Asian]]s and Blacks. It also occurs in [[Caucasian race|Caucasians]] and in young people.
| |
| | |
| ==Natural History, Complications, and Prognosis==
| |
| | |
| Any new area of pigmentation or an existing one that shows change should be checked by a [[dermatologist]]. If caught early this type of melanoma has a similar cure rate as the other types of superficial spreading melanoma.
| |
| | |
| ==Diagnosis==
| |
| ===Symptoms===
| |
| '''Typical symptoms include:'''
| |
| * longitudinal tan, black, or brown streak on a finger or toe nail ([[melanonychia striata]])
| |
| * pigmentation of proximal nail fold
| |
| * areas of dark pigmentation on palms of hands or soles of feet
| |
| ===Physical Examination===
| |
| This type of melanoma occurs on non hair baring surfaces of the body which may or may not be exposed to sunlight.
| |
| | |
| An example of a subungual melanoma is shown in the image below.
| |
| | |
| [http://www.peir.net Image shown below is courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology]
| |
| | |
| <div align="left">
| |
| <gallery heights="175" widths="175">
| |
| image:Subungual melanoma.jpg|This is a subungual radial growth phase of acral-lentiginous type with two amelanotic vertical growth phase tumor nodules. Radial growth phase is just beginning to grow onto the cuticle of the nail, displaying a subtle example of "Hutchinson's sign."
| |
| </gallery>
| |
| </div>
| |
| | |
| ==References==
| |
| {{Reflist|2}}
| |
| | |
| | |
| [[Category:pathology]]
| |
| [[Category:Types of cancer]]
| |
| | |
| | |
| | |
| {{WikiDoc Help Menu}}
| |
| {{WS}}
| |