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| __NOTOC__
| | #Redirect [[Melanoma]] |
| {{DiseaseDisorder infobox |
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| Name = Acral lentiginous melanoma |
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| ICD10 = C43 |
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| ICD9 = {{ICD9|172.0}}-{{ICD9|173.9}} |
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| ICDO = 8744/3 |
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| Image = Subungual melanoma|
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| }}
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| {{SI}}
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| {{CMG}}
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| ==Overview==
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| '''Acral lentiginous melanoma''' is a kind of skin [[melanoma]]. It is also known as subungual melanoma. It is seen on the palms, soles and under the nails.
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| ==Pathophysiology==
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| ===Microscopic Pathology===
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| '''The microscopic hallmarks are:'''
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| * Atypical [[melanocyte]]s in junctional nests
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| * [[Dermis|dermal]] invasion
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| * [[Desmoplasia]]
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| * [[Hyperplastic]] [[Epidermis (skin)|epidermis]]
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| ==Epidemiology and Demographics==
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| ===Age===
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| The average age at diagnosis is between sixty and seventy years.
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| ===Race===
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| This is the most common form of melanoma in [[Asian people|Asian]]s and Blacks. It also occurs in [[Caucasian race|Caucasians]] and in young people.
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| ==Natural History, Complications, and Prognosis==
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| Any new area of pigmentation or an existing one that shows change should be checked by a [[dermatologist]]. If caught early this type of melanoma has a similar cure rate as the other types of superficial spreading melanoma.
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| ==Diagnosis==
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| ===Symptoms===
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| '''Typical symptoms include:'''
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| * longitudinal tan, black, or brown streak on a finger or toe nail ([[melanonychia striata]])
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| * pigmentation of proximal nail fold
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| * areas of dark pigmentation on palms of hands or soles of feet
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| ===Physical Examination===
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| This type of melanoma occurs on non hair baring surfaces of the body which may or may not be exposed to sunlight.
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| An example of a subungual melanoma is shown in the image below.
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| [http://www.peir.net Image shown below is courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology]
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| <div align="left">
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| <gallery heights="175" widths="175">
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| image:Subungual melanoma.jpg|This is a subungual radial growth phase of acral-lentiginous type with two amelanotic vertical growth phase tumor nodules. Radial growth phase is just beginning to grow onto the cuticle of the nail, displaying a subtle example of "Hutchinson's sign."
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| </gallery>
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| </div>
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| ==References==
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| {{Reflist|2}}
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| [[Category:pathology]]
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| [[Category:Types of cancer]]
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