Acinic cell carcinoma natural history, complications and prognosis: Difference between revisions
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===Natural History=== | ===Natural History=== | ||
* Parotid gland, is the most common site for acinic cell carcinoma affection. | |||
* Typically, acinic cell carcinoma is a slow growing mass, lacking other symptoms. | |||
* Pain or fixation to surroundings is a sign of poor prognosis. | |||
* Nodal metastasis of acinic cell carcinoma is extremely rare. | |||
* Another rare complication is cranial nerve VII dysfunction. | |||
* A small minority of of acinic cell carcinoma occurs in sinonasal area or larynx. | |||
* There is a big controversy about bilateral acinic cell carcinoma, it is still unknown if it invades bilateral glands or just a unilateral tumor. | |||
* Common sites for non-salivary acinic cell carcinoma is lacrimal gland, pancreas, and breast. | |||
* Acinic cell carcinoma in pancreas are so called as acinar cell carcinoma. | |||
===Complications=== | ===Complications=== | ||
* growing mass in salivary glands | |||
* Pain | |||
* Fixation to surrounding tissue | |||
* Dysphagia | |||
* Hoarseness | |||
* Cranial nerve VII involvement | |||
* wight loss | |||
===Prognosis=== | ===Prognosis=== | ||
* Acinar cell carcinoma has the best prognosis out of all salivary gland carcinomas. | |||
* The worst prognosis subtype is high-grade transformation type. | |||
* Cure of acinic cell carcinoma prognosis varies from 89000 out of 100000 at 5 years to 55000 out of 100000 at 15 years. | |||
* Sever findings have suggested that a protracted cilinical course with reccurence occured years or even decades after initial diagnosis. | |||
* The prognostic factors are : | |||
** Age | |||
** Pain | |||
** Gender | |||
** Race | |||
** Perivious inadequate treatment | |||
** Extent of disease. | |||
** Invasion of the skull base. | |||
==References== | ==References== |
Revision as of 14:58, 16 September 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]
Overview
Natural History, Complications, and Prognosis
Natural History
- Parotid gland, is the most common site for acinic cell carcinoma affection.
- Typically, acinic cell carcinoma is a slow growing mass, lacking other symptoms.
- Pain or fixation to surroundings is a sign of poor prognosis.
- Nodal metastasis of acinic cell carcinoma is extremely rare.
- Another rare complication is cranial nerve VII dysfunction.
- A small minority of of acinic cell carcinoma occurs in sinonasal area or larynx.
- There is a big controversy about bilateral acinic cell carcinoma, it is still unknown if it invades bilateral glands or just a unilateral tumor.
- Common sites for non-salivary acinic cell carcinoma is lacrimal gland, pancreas, and breast.
- Acinic cell carcinoma in pancreas are so called as acinar cell carcinoma.
Complications
- growing mass in salivary glands
- Pain
- Fixation to surrounding tissue
- Dysphagia
- Hoarseness
- Cranial nerve VII involvement
- wight loss
Prognosis
- Acinar cell carcinoma has the best prognosis out of all salivary gland carcinomas.
- The worst prognosis subtype is high-grade transformation type.
- Cure of acinic cell carcinoma prognosis varies from 89000 out of 100000 at 5 years to 55000 out of 100000 at 15 years.
- Sever findings have suggested that a protracted cilinical course with reccurence occured years or even decades after initial diagnosis.
- The prognostic factors are :
- Age
- Pain
- Gender
- Race
- Perivious inadequate treatment
- Extent of disease.
- Invasion of the skull base.