Acinic cell carcinoma future or investigational therapies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]

Overview

Finding a good chemotherapy regimen for distant metastasis, molecular methodology by the concept of MASC, links between genetic and disease, the role of S-100 protein in salivary gland pathologies are fields of further research.

Future or Investigational Therapies

  • Finding a good chemotherapy regimen for distant metastasis is necessary, since far metastasis, specially lungs, have been involved in a great portion of patients.[1]
  • Molecular methodology by the concept of MASC need further thinking and research.
  • Links between genetic and disease is still uncertain.
  • The role of S-100 protein in salivary gland pathologies is still not very well understood.

References

  1. Vander Poorten, V.; Triantafyllou, A.; Thompson, L. D. R.; Bishop, J.; Hauben, E.; Hunt, J.; Skalova, A.; Stenman, G.; Takes, R. P.; Gnepp, D. R.; Hellquist, H.; Wenig, B.; Bell, D.; Rinaldo, A.; Ferlito, A. (2015). "Salivary acinic cell carcinoma: reappraisal and update". European Archives of Oto-Rhino-Laryngology. 273 (11): 3511–3531. doi:10.1007/s00405-015-3855-7. ISSN 0937-4477.

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