Acinic cell carcinoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]

Overview

Acinic cell carcinoma can appear at any age however, it is common in children.

• Acinic cell carcinoma appears in all age groups, but presents at a younger median age (approximately 52 years) than most other salivary gland cancers.
• Women are more frequently diagnosed than men.
• Occurrences in children are quite common.
• According to the National Cancer Data Base Report on cancer of the head and neck in the United States, the parotid gland was the predominant site of origin (86.3%) for reported acinic cell carcinoma.
• Regional and distant metastasis, high grade, and large tumor size were all more common among patients older than 30.
• No ethnic or racial predilection showed an association with acinic cell carcinoma.

Epidemiology and Demographics

Prevalence

In western countries, salivary gland carcinomas account for 4000 out of 100000 of all head and neck carcinomas, and approximately 80% of those occurring in parotid gland. one out of six parotid gland cancer is acinic cell carcinoma.