Achlorhydria (patient information)

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How do I know if I have achlorhydria and what are the symptoms of achlorhydria?

Patients with achlorhyria may have signs and aymptoms as the following:

• Impaired digestion or indigestion, undigested food in stools
• Nausea
• Bloating
• Diarrhea or constipation
• Increased susceptibility to bacterial and parasitic infection in stomach
• Iron deficiency
• Cracked nails

Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.

Who is at risk for achlorhydria?

• Prior gastric bypass surgery
• Chronic gastric H pylori infection
• Chronic proton pump inhibitor (PPI) use
• Autoimmune conditions, such as diabetes, autoimmune thyroid disease.
• Elderly individuals

How to know you have achlorhydria?

• Measurement of basal acid secretion and gastric pH: These are the most important and basic study to prove the presence of the condition of achlorhydria. In patients with achlorhydric, more than 50% of them whose initial stomach pH is 4.0 or higher.
• Gastrin levels: Serum gastrin level in patients with achlorhydria is very high. A serum gastrin levels higher than 500-1000 pg/mL may suggest a diagnosis of achlorhydria.
• Antiparietal cell antibody testing: Achlorhydria shows a strong association with autoimmune conditions. Many patients with achlorhydria can be detected antiparietal cell antibody.
• Blood tests: Blood tests such as iron indices, calcium, prothrombin time, vitamin B-12, vitamin D, serum folate, and thiamine levels should be checked to exclude deficiencies and anemia.
• Endoscopy and biopsy: Endoscopy is an very important test used in patients with suspected achlorhydria. This test can help find the cause of achlorhydria. During the procedure, after you are sedated, an endoscope which is a thin, flexible, lighted tube was passed down your throat. Then the doctor can view the lining of your esophagus, stomach, and first part of the small intestine. If abnormal areas are noted, biopsy can be obtained through the endoscope. The tissue samples will be checked by pathologist under a microscope to see what kind of change it is.

Where to find medical care for achlorhydria?

Directions to Hospitals Treating achlorhydria

Copyleft Sources

http://emedicine.medscape.com/article/170066-overview

http://www.wrongdiagnosis.com/a/achlorhydria/intro.htm

http://www.mdguidelines.com/achlorhydria-and-hypochlorhydria