Abdominal aortic aneurysm epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Aarti Narayan, M.B.B.S [3]

Overview

Abdominal aortic aneurysm is the 13th leading cause of death in the US.

Epidemiology and Demographics

Age

  • Abdominal aortic aneurysms (AAA) is a disease of the elderly, and is the 10th leading cause of death in older men in the United States.
  • An individual's risk of AAA increases by 6% per decade of life
  • Rupture of the AAA occurs in 1-3% of men aged 65 or more with an associated mortality rate of 70-95%[1].
  • AAA tends to cluster in families, therefore affecting younger members of families in the absence of traditional acquired risk factors.

Gender

  • The frequency rate varies strongly between males and females.
  • The peak incidence is among males around 70 years of age, the prevalence among males over 60 years totals 2-6%.
  • Other risk factors include hypertension and male sex.[2]
  • The prevalence is 2-5 times higher in men and 2-3 times higher in women with other cardiovascular risk factors or atherosclerotic cardiovascular diseases, than in control groups without risk factors.

Race

  • The disease tends to affect older Caucasian males.

Developed Countries

  • In the US, the incidence of AAA is 2-4% in the adult population.

Developing Countries

  • AAA is uncommon in individuals of African, African American, Asian and Hispanic heritage.

Other

  • The frequency is much higher in smokers than in non-smokers (8:1)

References

  1. Lindholt JS, Juul S, Fasting H, Henneberg EW. Screening for abdominal aortic aneurysms: single centre randomised controlled trial. BMJ 2005; 330: 750. PMCID: 555873
  2. Treska V. et al.:Aneuryzma břišní aorty, Prague, 1999, ISBN 80-7169-724-9

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