Abdominal aortic aneurysm epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Aarti Narayan, M.B.B.S [3]

Overview

Abdominal aortic aneurysm is the 13th leading cause of death in the US. Abdominal aortic aneurysms are more common in developed countries. Elderly, caucasian males who are smokers are at a higher risk for developing an abdominal aortic aneurysm.

Epidemiology and Demographics

Age

  • Abdominal aortic aneurysms (AAA) is a disease of the elderly, and is the 10th leading cause of death in older men in the United States.
  • An individual's risk of AAA increases by 6% per decade of life
  • Rupture of the AAA occurs in 1-3% of men aged 65 or more with an associated mortality rate of 70-95%.[1]
  • AAA tends to cluster in families, therefore affecting younger members of families in the absence of traditional acquired risk factors.

Gender

  • Abdominal aortic aneurysm is 5 times more common in men than women.
  • The peak incidence is among males around 70 years of age.
  • The prevalence among males over 60 years is 2000-6000/100,000.

Race

  • The disease tends to affect older Caucasian males and is 3.5 times more common in Caucasian men than in African-American men.

Developed Countries

  • In the US, the incidence of AAA is 2-4% in the adult population.

Developing Countries

  • AAA is uncommon in individuals of African, African American, Asian and Hispanic heritage.

Other

  • The frequency is much higher in smokers than in non-smokers (8:1).

References

  1. Lindholt JS, Juul S, Fasting H, Henneberg EW (2005). "Screening for abdominal aortic aneurysms: single centre randomised controlled trial". BMJ. 330 (7494): 750. doi:10.1136/bmj.38369.620162.82. PMC 555873. PMID 15757960. Review in: ACP J Club. 2005 Sep-Oct;143(2):39

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