Abdominal aortic aneurysm epidemiology and demographics: Difference between revisions

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__NOTOC__
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{{Template:Abdominal aortic aneurysm}}
{{Template:Abdominal aortic aneurysm}}
{{CMG}} '''Associate Editor-In-Chief:''' {{CZ}}, {{AN}}
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}; {{AN}}


==Overview==
==Overview==
[[Abdominal aortic aneurysm]] is the 13th leading cause of [[death]] in the US.
[[Abdominal aortic aneurysm]] is the 13th leading cause of [[death]] in the US.  Abdominal aortic aneurysms are more common in developed countries. Elderly, caucasian males who are smokers are at a higher risk for developing an abdominal aortic aneurysm.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence ===
* The incidence of abdominal aortic aneurysms increases after age 60 and peaks in the seventh and eighth decades of life.<ref name="ZommorodiLeander2018">{{cite journal|last1=Zommorodi|first1=Sayid|last2=Leander|first2=Karin|last3=Roy|first3=Joy|last4=Steuer|first4=Johnny|last5=Hultgren|first5=Rebecka|title=Understanding abdominal aortic aneurysm epidemiology: socioeconomic position affects outcome|journal=Journal of Epidemiology and Community Health|volume=72|issue=10|year=2018|pages=904–910|issn=0143-005X|doi=10.1136/jech-2018-210644}}</ref>
=== Prevalence ===
* The [[prevalence]] among males over 60 years is 2000-6000/100,000.<ref name="AndersonShiralkar2008">{{cite journal|last1=Anderson|first1=Oliver|last2=Shiralkar|first2=Sandy|title=Prevalence of Abdominal Aortic Aneurysms in Over 65-Year-Old Men with Inguinal Hernias|journal=The Annals of The Royal College of Surgeons of England|volume=90|issue=5|year=2008|pages=386–388|issn=0035-8843|doi=10.1308/003588408X285937}}</ref>


===Age===
===Age===
* Abdominal aortic aneurysms (AAA) is a disease of the elderly, and is the 10th leading cause of death in older men in the United States.
*Abdominal aortic aneurysms (AAA) is a disease of the elderly, and is the 10th leading cause of death in older men in the United States.<ref name="UmebayashiUchida2018">{{cite journal|last1=Umebayashi|first1=Ryoko|last2=Uchida|first2=Haruhito A.|last3=Wada|first3=Jun|title=Abdominal aortic aneurysm in aged population|journal=Aging|volume=10|issue=12|year=2018|pages=3650–3651|issn=1945-4589|doi=10.18632/aging.101702}}</ref>
* An individual's risk of AAA increases by 6% per decade of life
*An individual's risk of AAA increases by 6% per decade of life
* Rupture of the AAA occurs in 1-3% of men aged 65 or more with an associated mortality rate of 70-95%<ref name="screening">Lindholt JS, Juul S, Fasting H, Henneberg EWScreening for abdominal aortic aneurysms: single centre randomised controlled trial. ''BMJ'' 2005; '''330''': 750. PMCID: 555873</ref>.
*Rupture of the AAA occurs in 1-3% of men aged 65 or more with an associated mortality rate of 70-95%.<ref name="pmid15757960">{{cite journal| author=Lindholt JS, Juul S, Fasting H, Henneberg EW| title=Screening for abdominal aortic aneurysms: single centre randomised controlled trial. | journal=BMJ | year= 2005 | volume= 330 | issue= 7494 | pages= 750 | pmid=15757960 | doi=10.1136/bmj.38369.620162.82 | pmc=PMC555873 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15757960  }}  [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16134913 Review in: ACP J Club. 2005 Sep-Oct;143(2):39] </ref>
* AAA tends to cluster in families, therefore affecting younger members of families in the absence of traditional acquired risk factors.
*AAA tends to cluster in families, therefore affecting younger members of families in the absence of traditional acquired risk factors.


===Gender===
===Gender===
* The frequency rate varies strongly between males and females.
*Abdominal aortic aneurysm is 5 times more common in men than women.<ref name="pmid19426607">{{cite journal| author=Hannawa KK, Eliason JL, Upchurch GR| title=Gender differences in abdominal aortic aneurysms. | journal=Vascular | year= 2009 | volume= 17 Suppl 1 | issue=  | pages= S30-9 | pmid=19426607 | doi=10.2310/6670.2008.00092 | pmc=2913052 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19426607  }}</ref>
* The peak [[incidence]] is among males around 70 years of age, the [[prevalence]] among males over 60 years totals 2-6%.
* It is 5 times more common in men than women.


===Race===
===Race===
* The disease tends to affect older Caucasian males.
*The disease tends to affect older Caucasian males and is 3.5 times more common in Caucasian men than in African-American men.<ref name="Lackland2014">{{cite journal|last1=Lackland|first1=Daniel T.|title=Racial Differences in Hypertension: Implications for High Blood Pressure Management|journal=The American Journal of the Medical Sciences|volume=348|issue=2|year=2014|pages=135–138|issn=00029629|doi=10.1097/MAJ.0000000000000308}}</ref>


===Developed Countries===
===Developed Countries===
* In the US, the incidence of AAA is 2-4% in the adult population.
*In the US, the incidence of abdominal aortic aneurysm is 2-4% in the adult population.<ref name="FolliLi2013">{{cite journal|last1=Folli|first1=Franco|last2=Li|first2=Xi|last3=Zhao|first3=Ge|last4=Zhang|first4=Jian|last5=Duan|first5=Zhiquan|last6=Xin|first6=Shijie|title=Prevalence and Trends of the Abdominal Aortic Aneurysms Epidemic in General Population - A Meta-Analysis|journal=PLoS ONE|volume=8|issue=12|year=2013|pages=e81260|issn=1932-6203|doi=10.1371/journal.pone.0081260}}</ref>


===Developing Countries===
===Developing Countries===
* AAA is uncommon in individuals of African, African American, Asian and Hispanic heritage.
*Abdominal aortic aneurysm is uncommon in individuals of African, African American, Asian and Hispanic heritage.<ref name="pmid29262134">{{cite journal| author=| title=StatPearls | journal= | year= 2019 | volume=  | issue=  | pages=  | pmid=29262134 | doi= | pmc= | url= }}</ref>


===Other===
===Other===
* The frequency is much higher in [[smoking|smokers]] than in non-smokers (8:1)
*The frequency of abdominal aortic aneurysm is much higher in [[smoking|smokers]] than in non-smokers (8:1).<ref name="AuneSchlesinger2018">{{cite journal|last1=Aune|first1=Dagfinn|last2=Schlesinger|first2=Sabrina|last3=Norat|first3=Teresa|last4=Riboli|first4=Elio|title=Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies|journal=Scientific Reports|volume=8|issue=1|year=2018|issn=2045-2322|doi=10.1038/s41598-018-32100-2}}</ref>


==References==
==References==
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Latest revision as of 21:54, 6 January 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Aarti Narayan, M.B.B.S [3]

Overview

Abdominal aortic aneurysm is the 13th leading cause of death in the US. Abdominal aortic aneurysms are more common in developed countries. Elderly, caucasian males who are smokers are at a higher risk for developing an abdominal aortic aneurysm.

Epidemiology and Demographics

Incidence

  • The incidence of abdominal aortic aneurysms increases after age 60 and peaks in the seventh and eighth decades of life.[1]

Prevalence

  • The prevalence among males over 60 years is 2000-6000/100,000.[2]

Age

  • Abdominal aortic aneurysms (AAA) is a disease of the elderly, and is the 10th leading cause of death in older men in the United States.[3]
  • An individual's risk of AAA increases by 6% per decade of life
  • Rupture of the AAA occurs in 1-3% of men aged 65 or more with an associated mortality rate of 70-95%.[4]
  • AAA tends to cluster in families, therefore affecting younger members of families in the absence of traditional acquired risk factors.

Gender

  • Abdominal aortic aneurysm is 5 times more common in men than women.[5]

Race

  • The disease tends to affect older Caucasian males and is 3.5 times more common in Caucasian men than in African-American men.[6]

Developed Countries

  • In the US, the incidence of abdominal aortic aneurysm is 2-4% in the adult population.[7]

Developing Countries

  • Abdominal aortic aneurysm is uncommon in individuals of African, African American, Asian and Hispanic heritage.[8]

Other

  • The frequency of abdominal aortic aneurysm is much higher in smokers than in non-smokers (8:1).[9]

References

  1. Zommorodi, Sayid; Leander, Karin; Roy, Joy; Steuer, Johnny; Hultgren, Rebecka (2018). "Understanding abdominal aortic aneurysm epidemiology: socioeconomic position affects outcome". Journal of Epidemiology and Community Health. 72 (10): 904–910. doi:10.1136/jech-2018-210644. ISSN 0143-005X.
  2. Anderson, Oliver; Shiralkar, Sandy (2008). "Prevalence of Abdominal Aortic Aneurysms in Over 65-Year-Old Men with Inguinal Hernias". The Annals of The Royal College of Surgeons of England. 90 (5): 386–388. doi:10.1308/003588408X285937. ISSN 0035-8843.
  3. Umebayashi, Ryoko; Uchida, Haruhito A.; Wada, Jun (2018). "Abdominal aortic aneurysm in aged population". Aging. 10 (12): 3650–3651. doi:10.18632/aging.101702. ISSN 1945-4589.
  4. Lindholt JS, Juul S, Fasting H, Henneberg EW (2005). "Screening for abdominal aortic aneurysms: single centre randomised controlled trial". BMJ. 330 (7494): 750. doi:10.1136/bmj.38369.620162.82. PMC 555873. PMID 15757960. Review in: ACP J Club. 2005 Sep-Oct;143(2):39
  5. Hannawa KK, Eliason JL, Upchurch GR (2009). "Gender differences in abdominal aortic aneurysms". Vascular. 17 Suppl 1: S30–9. doi:10.2310/6670.2008.00092. PMC 2913052. PMID 19426607.
  6. Lackland, Daniel T. (2014). "Racial Differences in Hypertension: Implications for High Blood Pressure Management". The American Journal of the Medical Sciences. 348 (2): 135–138. doi:10.1097/MAJ.0000000000000308. ISSN 0002-9629.
  7. Folli, Franco; Li, Xi; Zhao, Ge; Zhang, Jian; Duan, Zhiquan; Xin, Shijie (2013). "Prevalence and Trends of the Abdominal Aortic Aneurysms Epidemic in General Population - A Meta-Analysis". PLoS ONE. 8 (12): e81260. doi:10.1371/journal.pone.0081260. ISSN 1932-6203.
  8. "StatPearls". 2019. PMID 29262134.
  9. Aune, Dagfinn; Schlesinger, Sabrina; Norat, Teresa; Riboli, Elio (2018). "Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies". Scientific Reports. 8 (1). doi:10.1038/s41598-018-32100-2. ISSN 2045-2322.

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