ARHGDIG: Difference between revisions

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

VisualWikitext

Latest revision as of 18:13, 29 August 2017

Rho GDP-dissociation inhibitor 3 is a protein that in humans is encoded by the ARHGDIG gene.^[1]^[2]^[3]

Interactions

ARHGDIG has been shown to interact with RHOB.^[4]

References

↑ Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L, Cerione RA, Lim B (May 1997). "RhoGDIγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas". Proc Natl Acad Sci U S A. 94 (9): 4279–84. doi:10.1073/pnas.94.9.4279. PMC 20713. PMID 9113980.
↑ Brunet N, Morin A, Olofsson B (Apr 2002). "RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain". Traffic. 3 (5): 342–57. doi:10.1034/j.1600-0854.2002.30504.x. PMID 11967128.
↑ "Entrez Gene: ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma".
↑ Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A, Olofsson B (Nov 1996). "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. 271 (48): 30366–74. doi:10.1074/jbc.271.48.30366. PMID 8939998.

External links

Human ARHGDIG genome location and ARHGDIG gene details page in the UCSC Genome Browser.

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A, Olofsson B (1997). "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. 271 (48): 30366–74. doi:10.1074/jbc.271.48.30366. PMID 8939998.
Adra CN, Iyengar AR, Syed FA, Kanaan IN, Rilo HL, Yu W, Kheraj R, Lin SR, Horiuchi T, Khan S, Weremowicz S, Lim B, Morton CC, Higgs DR (1998). "Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3". Genomics. 53 (1): 104–9. doi:10.1006/geno.1998.5482. PMID 9787082.
Elenich LA, Nandi D, Kent AE, McCluskey TS, Cruz M, Iyer MN, Woodward EC, Conn CW, Ochoa AL, Ginsburg DB, Monaco JJ (1999). "The complete primary structure of mouse 20S proteasomes". Immunogenetics. 49 (10): 835–42. doi:10.1007/s002510050562. PMID 10436176.
Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C, Kearney L, Buckle VJ, Doggett NA, Flint J, Higgs DR (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
Li X, Bu X, Lu B, Avraham H, Flavell RA, Lim B (2002). "The Hematopoiesis-Specific GTP-Binding Protein RhoH Is GTPase Deficient and Modulates Activities of Other Rho GTPases by an Inhibitory Function". Mol. Cell. Biol. 22 (4): 1158–71. doi:10.1128/MCB.22.4.1158-1171.2002. PMC 134637. PMID 11809807.
del Pozo MA, Alderson NB, Kiosses WB, Chiang HH, Anderson RG, Schwartz MA (2004). "Integrins regulate Rac targeting by internalization of membrane domains". Science. 303 (5659): 839–42. doi:10.1126/science.1092571. PMID 14764880.
Dransart E, Morin A, Cherfils J, Olofsson B (2005). "Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors". J. Biol. Chem. 280 (6): 4674–83. doi:10.1074/jbc.M409741200. PMID 15513926.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[pmid9113980-1] Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L, Cerione RA, Lim B (May 1997). "RhoGDIγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas". Proc Natl Acad Sci U S A. 94 (9): 4279–84. doi:10.1073/pnas.94.9.4279. PMC 20713. PMID 9113980.

[pmid11967128-2] Brunet N, Morin A, Olofsson B (Apr 2002). "RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain". Traffic. 3 (5): 342–57. doi:10.1034/j.1600-0854.2002.30504.x. PMID 11967128.

[entrez-3] "Entrez Gene: ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma".

[pmid8939998-4] Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A, Olofsson B (Nov 1996). "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. 271 (48): 30366–74. doi:10.1074/jbc.271.48.30366. PMID 8939998.

[1]

[2]

[3]

[4]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Rho GDP-dissociation inhibitor 3''' is a [[protein]] that in humans is encoded by the ''ARHGDIG'' [[gene]].<ref name="pmid9113980">{{cite journal | vauthors = Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L, Cerione RA, Lim B | title = RhoGDIγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas | journal = Proc Natl Acad Sci U S A | volume = 94 | issue = 9 | pages = 4279–84 | date = May 1997 | pmid = 9113980 | pmc = 20713 | doi = 10.1073/pnas.94.9.4279 }}</ref><ref name="pmid11967128">{{cite journal | vauthors = Brunet N, Morin A, Olofsson B | title = RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain | journal = Traffic | volume = 3 | issue = 5 | pages = 342–57 | date = Apr 2002 | pmid = 11967128 | pmc =  | doi = 10.1034/j.1600-0854.2002.30504.x }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=398| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Rho GDP dissociation inhibitor (GDI) gamma
- | HGNCid = 680
- | Symbol = ARHGDIG
- | AltSymbols =; RHOGDI-3
- | OMIM = 602844
- | ECnumber =
- | Homologene = 7337
- | MGIid = 108430
- | GeneAtlas_image1 = PBB_GE_ARHGDIG_206888_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_ARHGDIG_206889_at_tn.png
- | Function = {{GNF_GO|id=GO:0005094 |text = Rho GDP-dissociation inhibitor activity}} {{GNF_GO|id=GO:0005096 |text = GTPase activator activity}}
- | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0016023 |text = cytoplasmic membrane-bound vesicle}}
- | Process = {{GNF_GO|id=GO:0007162 |text = negative regulation of cell adhesion}} {{GNF_GO|id=GO:0007266 |text = Rho protein signal transduction}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 398
-    | Hs_Ensembl = ENSG00000206156
-    | Hs_RefseqProtein = NP_001167
-    | Hs_RefseqmRNA = NM_001176
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 16
-    | Hs_GenLoc_start = 270682
-    | Hs_GenLoc_end = 272815
-    | Hs_Uniprot = Q99819
-    | Mm_EntrezGene = 14570
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA = NM_008113
-    | Mm_RefseqProtein = NP_032139
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''Rho GDP dissociation inhibitor (GDI) gamma''', also known as '''ARHGDIG''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=398| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+ARHGDIG has been shown to [[Protein-protein interaction|interact]] with [[RHOB]].<ref name=pmid8939998>{{cite journal | vauthors = Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A, Olofsson B | title = RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG | journal = J. Biol. Chem. | volume = 271 | issue = 48 | pages = 30366–74 | date = Nov 1996 | pmid = 8939998 | doi = 10.1074/jbc.271.48.30366 }}</ref>
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
-==Further reading==
+==External links==
+* {{UCSC gene info|ARHGDIG}}
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Res. | volume = 6 | issue = 9 | pages = 791–806 | year = 1997 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 }}
-| citations =
+* {{cite journal | vauthors = Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A, Olofsson B | title = RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG | journal = J. Biol. Chem. | volume = 271 | issue = 48 | pages = 30366–74 | year = 1997 | pmid = 8939998 | doi = 10.1074/jbc.271.48.30366 }}
-*{{cite journal  | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
+* {{cite journal | vauthors = Adra CN, Iyengar AR, Syed FA, Kanaan IN, Rilo HL, Yu W, Kheraj R, Lin SR, Horiuchi T, Khan S, Weremowicz S, Lim B, Morton CC, Higgs DR | title = Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3 | journal = Genomics | volume = 53 | issue = 1 | pages = 104–9 | year = 1998 | pmid = 9787082 | doi = 10.1006/geno.1998.5482 }}
-*{{cite journal  | author=Zalcman G, Closson V, Camonis J, ''et al.'' |title=RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG. |journal=J. Biol. Chem. |volume=271 |issue= 48 |pages= 30366-74 |year= 1997 |pmid= 8939998 |doi=  }}
+* {{cite journal | vauthors = Elenich LA, Nandi D, Kent AE, McCluskey TS, Cruz M, Iyer MN, Woodward EC, Conn CW, Ochoa AL, Ginsburg DB, Monaco JJ | title = The complete primary structure of mouse 20S proteasomes | journal = Immunogenetics | volume = 49 | issue = 10 | pages = 835–42 | year = 1999 | pmid = 10436176 | doi = 10.1007/s002510050562 }}
-*{{cite journal  | author=Adra CN, Manor D, Ko JL, ''et al.'' |title=RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 9 |pages= 4279-84 |year= 1997 |pmid= 9113980 |doi=  }}
+* {{cite journal | vauthors = Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C, Kearney L, Buckle VJ, Doggett NA, Flint J, Higgs DR | title = Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16 | journal = Hum. Mol. Genet. | volume = 10 | issue = 4 | pages = 339–52 | year = 2001 | pmid = 11157797 | doi = 10.1093/hmg/10.4.339 }}
-*{{cite journal  | author=Adra CN, Iyengar AR, Syed FA, ''et al.'' |title=Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3. |journal=Genomics |volume=53 |issue= 1 |pages= 104-9 |year= 1998 |pmid= 9787082 |doi=  }}
+* {{cite journal | vauthors = Li X, Bu X, Lu B, Avraham H, Flavell RA, Lim B | title = The Hematopoiesis-Specific GTP-Binding Protein RhoH Is GTPase Deficient and Modulates Activities of Other Rho GTPases by an Inhibitory Function | journal = Mol. Cell. Biol. | volume = 22 | issue = 4 | pages = 1158–71 | year = 2002 | pmid = 11809807 | pmc = 134637 | doi = 10.1128/MCB.22.4.1158-1171.2002 }}
-*{{cite journal  | author=Elenich LA, Nandi D, Kent AE, ''et al.'' |title=The complete primary structure of mouse 20S proteasomes. |journal=Immunogenetics |volume=49 |issue= 10 |pages= 835-42 |year= 1999 |pmid= 10436176 |doi=  }}
+* {{cite journal | vauthors = del Pozo MA, Alderson NB, Kiosses WB, Chiang HH, Anderson RG, Schwartz MA | title = Integrins regulate Rac targeting by internalization of membrane domains | journal = Science | volume = 303 | issue = 5659 | pages = 839–42 | year = 2004 | pmid = 14764880 | doi = 10.1126/science.1092571 }}
-*{{cite journal  | author=Daniels RJ, Peden JF, Lloyd C, ''et al.'' |title=Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 339-52 |year= 2001 |pmid= 11157797 |doi=  }}
+* {{cite journal | vauthors = Dransart E, Morin A, Cherfils J, Olofsson B | title = Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors | journal = J. Biol. Chem. | volume = 280 | issue = 6 | pages = 4674–83 | year = 2005 | pmid = 15513926 | doi = 10.1074/jbc.M409741200 }}
-*{{cite journal  | author=Li X, Bu X, Lu B, ''et al.'' |title=The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function. |journal=Mol. Cell. Biol. |volume=22 |issue= 4 |pages= 1158-71 |year= 2002 |pmid= 11809807 |doi=  }}
-*{{cite journal  | author=Brunet N, Morin A, Olofsson B |title=RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain. |journal=Traffic |volume=3 |issue= 5 |pages= 342-57 |year= 2002 |pmid= 11967128 |doi=  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=del Pozo MA, Alderson NB, Kiosses WB, ''et al.'' |title=Integrins regulate Rac targeting by internalization of membrane domains. |journal=Science |volume=303 |issue= 5659 |pages= 839-42 |year= 2004 |pmid= 14764880 |doi= 10.1126/science.1092571 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Dransart E, Morin A, Cherfils J, Olofsson B |title=Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors. |journal=J. Biol. Chem. |volume=280 |issue= 6 |pages= 4674-83 |year= 2005 |pmid= 15513926 |doi= 10.1074/jbc.M409741200 }}
-*{{cite journal  | author=Martin J, Han C, Gordon LA, ''et al.'' |title=The sequence and analysis of duplication-rich human chromosome 16. |journal=Nature |volume=432 |issue= 7020 |pages= 988-94 |year= 2005 |pmid= 15616553 |doi= 10.1038/nature03187 }}
-}}
 {{refend}}
-{{protein-stub}}
-{{WikiDoc Sources}}
+{{gene-16-stub}}

ARHGDIG: Difference between revisions

Latest revision as of 18:13, 29 August 2017

Contents

Interactions

References

External links

Further reading

Navigation menu