AP2B1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''AP-2 complex subunit beta''' is a [[protein]] that in humans is encoded by the ''AP2B1'' [[gene]].<ref name="pmid8262066">{{cite journal | vauthors = Gallusser A, Kirchhausen T | title = The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components | journal = The EMBO Journal | volume = 12 | issue = 13 | pages = 5237–44 | date = Dec 1993 | pmid = 8262066 | pmc = 413789 | doi =  }}</ref><ref name="pmid8595912">{{cite journal | vauthors = Druck T, Gu Y, Prabhala G, Cannizzaro LA, Park SH, Huebner K, Keen JH | title = Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP | journal = Genomics | volume = 30 | issue = 1 | pages = 94–7 | date = Nov 1995 | pmid = 8595912 | pmc =  | doi = 10.1006/geno.1995.0016 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AP2B1 adaptor-related protein complex 2, beta 1 subunit| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=163| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image = PBB_Protein_AP2B1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1e42.
| PDB = {{PDB2|1e42}}, {{PDB2|1gw5}}, {{PDB2|1w63}}, {{PDB2|2g30}}, {{PDB2|2iv9}}
| Name = Adaptor-related protein complex 2, beta 1 subunit
| HGNCid = 563
| Symbol = AP2B1
| AltSymbols =; ADTB2; AP105B; AP2-BETA; CLAPB1; DKFZp781K0743
| OMIM = 601025
| ECnumber = 
| Homologene = 68176
| MGIid = 1919020
| GeneAtlas_image1 = PBB_GE_AP2B1_200615_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005488 |text = binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005905 |text = coated pit}} {{GNF_GO|id=GO:0030130 |text = clathrin coat of trans-Golgi network vesicle}}
| Process = {{GNF_GO|id=GO:0006461 |text = protein complex assembly}} {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 163
    | Hs_Ensembl = ENSG00000006125
    | Hs_RefseqProtein = NP_001025177
    | Hs_RefseqmRNA = NM_001030006
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 30938395
    | Hs_GenLoc_end = 31077547
    | Hs_Uniprot = P63010
    | Mm_EntrezGene = 71770
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = NM_001035854
    | Mm_RefseqProtein = NP_001030931
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Adaptor-related protein complex 2, beta 1 subunit''', also known as '''AP2B1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: AP2B1 adaptor-related protein complex 2, beta 1 subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=163| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The protein encoded by this gene is one of two large chain components of the [[AP2 adaptor complex]], which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: AP2B1 adaptor-related protein complex 2, beta 1 subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=163| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
AP2B1 has been shown to [[Protein-protein interaction|interact]] with:
{{div col|colwidth=20em}}
* [[AP1M2]],<ref name = pmid16189514>{{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}</ref>
* [[Arrestin beta 2]],<ref name = pmid10097102>{{cite journal | vauthors = Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS | title = The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 96 | issue = 7 | pages = 3712–7 | date = Mar 1999 | pmid = 10097102 | pmc = 22359 | doi =  10.1073/pnas.96.7.3712}}</ref><ref name = pmid12070169>{{cite journal | vauthors = Kim YM, Benovic JL | title = Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking | journal = The Journal of Biological Chemistry | volume = 277 | issue = 34 | pages = 30760–8 | date = Aug 2002 | pmid = 12070169 | doi = 10.1074/jbc.M204528200 }}</ref>
* [[BUB1B]],<ref name = pmid12419313>{{cite journal | vauthors = Cayrol C, Cougoule C, Wright M | title = The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1 | journal = Biochemical and Biophysical Research Communications | volume = 298 | issue = 5 | pages = 720–30 | date = Nov 2002 | pmid = 12419313 | doi =  10.1016/s0006-291x(02)02522-6}}</ref>
* [[LDLRAP1]]<ref name = pmid16189514/><ref name = pmid12221107>{{cite journal | vauthors = He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC | title = ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 46 | pages = 44044–9 | date = Nov 2002 | pmid = 12221107 | doi = 10.1074/jbc.M208539200 }}</ref>  and
* [[TGF beta receptor 2]].<ref name = pmid12429842>{{cite journal | vauthors = Yao D, Ehrlich M, Henis YI, Leof EB | title = Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit | journal = Molecular Biology of the Cell | volume = 13 | issue = 11 | pages = 4001–12 | date = Nov 2002 | pmid = 12429842 | pmc = 133610 | doi = 10.1091/mbc.02-07-0104 }}</ref>
{{Div col end}}
 
== References ==
{{reflist}}
{{Clear}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Kirchhausen T | title = Clathrin | journal = Annual Review of Biochemistry | volume = 69 | issue =  | pages = 699–727 | year = 2000 | pmid = 10966473 | doi = 10.1146/annurev.biochem.69.1.699 }}
| citations =
* {{cite journal | vauthors = Geyer M, Fackler OT, Peterlin BM | title = Structure--function relationships in HIV-1 Nef | journal = EMBO Reports | volume = 2 | issue = 7 | pages = 580–5 | date = Jul 2001 | pmid = 11463741 | pmc = 1083955 | doi = 10.1093/embo-reports/kve141 }}
*{{cite journal | author=Kirchhausen T |title=Clathrin. |journal=Annu. Rev. Biochem. |volume=69 |issue=  |pages= 699-727 |year= 2000 |pmid= 10966473 |doi= 10.1146/annurev.biochem.69.1.699 }}
* {{cite journal | vauthors = Ponnambalam S, Robinson MS, Jackson AP, Peiperl L, Parham P | title = Conservation and diversity in families of coated vesicle adaptins | journal = The Journal of Biological Chemistry | volume = 265 | issue = 9 | pages = 4814–20 | date = Mar 1990 | pmid = 1969413 | doi =  }}
*{{cite journal | author=Geyer M, Fackler OT, Peterlin BM |title=Structure--function relationships in HIV-1 Nef. |journal=EMBO Rep. |volume=2 |issue= 7 |pages= 580-5 |year= 2001 |pmid= 11463741 |doi= 10.1093/embo-reports/kve141 }}
* {{cite journal | vauthors = Greenberg ME, Bronson S, Lock M, Neumann M, Pavlakis GN, Skowronski J | title = Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation | journal = The EMBO Journal | volume = 16 | issue = 23 | pages = 6964–76 | date = Dec 1997 | pmid = 9384576 | pmc = 1170300 | doi = 10.1093/emboj/16.23.6964 }}
*{{cite journal | author=Ponnambalam S, Robinson MS, Jackson AP, ''et al.'' |title=Conservation and diversity in families of coated vesicle adaptins. |journal=J. Biol. Chem. |volume=265 |issue= 9 |pages= 4814-20 |year= 1990 |pmid= 1969413 |doi=  }}
* {{cite journal | vauthors = Lim DS, Kirsch DG, Canman CE, Ahn JH, Ziv Y, Newman LS, Darnell RB, Shiloh Y, Kastan MB | title = ATM binds to beta-adaptin in cytoplasmic vesicles | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 17 | pages = 10146–51 | date = Aug 1998 | pmid = 9707615 | pmc = 21476 | doi = 10.1073/pnas.95.17.10146 }}
*{{cite journal | author=Gallusser A, Kirchhausen T |title=The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components. |journal=EMBO J. |volume=12 |issue= 13 |pages= 5237-44 |year= 1994 |pmid= 8262066 |doi=  }}
* {{cite journal | vauthors = Greenberg M, DeTulleo L, Rapoport I, Skowronski J, Kirchhausen T | title = A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4 | journal = Current Biology | volume = 8 | issue = 22 | pages = 1239–42 | date = Nov 1998 | pmid = 9811611 | doi = 10.1016/S0960-9822(07)00518-0 }}
*{{cite journal  | author=Druck T, Gu Y, Prabhala G, ''et al.'' |title=Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP. |journal=Genomics |volume=30 |issue= 1 |pages= 94-7 |year= 1996 |pmid= 8595912 |doi= 10.1006/geno.1995.0016 }}
* {{cite journal | vauthors = Berlioz-Torrent C, Shacklett BL, Erdtmann L, Delamarre L, Bouchaert I, Sonigo P, Dokhelar MC, Benarous R | title = Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins | journal = Journal of Virology | volume = 73 | issue = 2 | pages = 1350–61 | date = Feb 1999 | pmid = 9882340 | pmc = 103959 | doi =  }}
*{{cite journal  | author=Greenberg ME, Bronson S, Lock M, ''et al.'' |title=Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. |journal=EMBO J. |volume=16 |issue= 23 |pages= 6964-76 |year= 1998 |pmid= 9384576 |doi= 10.1093/emboj/16.23.6964 }}
* {{cite journal | vauthors = Owen DJ, Vallis Y, Pearse BM, McMahon HT, Evans PR | title = The structure and function of the beta 2-adaptin appendage domain | journal = The EMBO Journal | volume = 19 | issue = 16 | pages = 4216–27 | date = Aug 2000 | pmid = 10944104 | pmc = 302036 | doi = 10.1093/emboj/19.16.4216 }}
*{{cite journal | author=Lim DS, Kirsch DG, Canman CE, ''et al.'' |title=ATM binds to beta-adaptin in cytoplasmic vesicles. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 17 |pages= 10146-51 |year= 1998 |pmid= 9707615 |doi= }}
* {{cite journal | vauthors = Fan GH, Yang W, Wang XJ, Qian Q, Richmond A | title = Identification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalization | journal = Biochemistry | volume = 40 | issue = 3 | pages = 791–800 | date = Jan 2001 | pmid = 11170396 | pmc = 2664867 | doi = 10.1021/bi001661b }}
*{{cite journal | author=Greenberg M, DeTulleo L, Rapoport I, ''et al.'' |title=A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. |journal=Curr. Biol. |volume=8 |issue= 22 |pages= 1239-42 |year= 1999 |pmid= 9811611 |doi= }}
* {{cite journal | vauthors = Swigut T, Shohdy N, Skowronski J | title = Mechanism for down-regulation of CD28 by Nef | journal = The EMBO Journal | volume = 20 | issue = 7 | pages = 1593–604 | date = Apr 2001 | pmid = 11285224 | pmc = 145469 | doi = 10.1093/emboj/20.7.1593 }}
*{{cite journal | author=Berlioz-Torrent C, Shacklett BL, Erdtmann L, ''et al.'' |title=Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins. |journal=J. Virol. |volume=73 |issue= 2 |pages= 1350-61 |year= 1999 |pmid= 9882340 |doi=  }}
* {{cite journal | vauthors = Laporte SA, Miller WE, Kim KM, Caron MG | title = beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin | journal = The Journal of Biological Chemistry | volume = 277 | issue = 11 | pages = 9247–54 | date = Mar 2002 | pmid = 11777907 | doi = 10.1074/jbc.M108490200 }}
*{{cite journal | author=Owen DJ, Vallis Y, Pearse BM, ''et al.'' |title=The structure and function of the beta 2-adaptin appendage domain. |journal=EMBO J. |volume=19 |issue= 16 |pages= 4216-27 |year= 2000 |pmid= 10944104 |doi= 10.1093/emboj/19.16.4216 }}
* {{cite journal | vauthors = Collins BM, McCoy AJ, Kent HM, Evans PR, Owen DJ | title = Molecular architecture and functional model of the endocytic AP2 complex | journal = Cell | volume = 109 | issue = 4 | pages = 523–35 | date = May 2002 | pmid = 12086608 | doi = 10.1016/S0092-8674(02)00735-3 }}
*{{cite journal | author=Fan GH, Yang W, Wang XJ, ''et al.'' |title=Identification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalization. |journal=Biochemistry |volume=40 |issue= 3 |pages= 791-800 |year= 2001 |pmid= 11170396 |doi= }}
* {{cite journal | vauthors = He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC | title = ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 46 | pages = 44044–9 | date = Nov 2002 | pmid = 12221107 | doi = 10.1074/jbc.M208539200 }}
*{{cite journal | author=Swigut T, Shohdy N, Skowronski J |title=Mechanism for down-regulation of CD28 by Nef. |journal=EMBO J. |volume=20 |issue= 7 |pages= 1593-604 |year= 2001 |pmid= 11285224 |doi= 10.1093/emboj/20.7.1593 }}
* {{cite journal | vauthors = Cayrol C, Cougoule C, Wright M | title = The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1 | journal = Biochemical and Biophysical Research Communications | volume = 298 | issue = 5 | pages = 720–30 | date = Nov 2002 | pmid = 12419313 | doi = 10.1016/S0006-291X(02)02522-6 }}
*{{cite journal | author=Laporte SA, Miller WE, Kim KM, Caron MG |title=beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin. |journal=J. Biol. Chem. |volume=277 |issue= 11 |pages= 9247-54 |year= 2002 |pmid= 11777907 |doi= 10.1074/jbc.M108490200 }}
* {{cite journal | vauthors = Yao D, Ehrlich M, Henis YI, Leof EB | title = Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit | journal = Molecular Biology of the Cell | volume = 13 | issue = 11 | pages = 4001–12 | date = Nov 2002 | pmid = 12429842 | pmc = 133610 | doi = 10.1091/mbc.02-07-0104 }}
*{{cite journal | author=Collins BM, McCoy AJ, Kent HM, ''et al.'' |title=Molecular architecture and functional model of the endocytic AP2 complex. |journal=Cell |volume=109 |issue= 4 |pages= 523-35 |year= 2002 |pmid= 12086608 |doi= }}
* {{cite journal | vauthors = Kalthoff C, Groos S, Kohl R, Mahrhold S, Ungewickell EJ | title = Clint: a novel clathrin-binding ENTH-domain protein at the Golgi | journal = Molecular Biology of the Cell | volume = 13 | issue = 11 | pages = 4060–73 | date = Nov 2002 | pmid = 12429846 | pmc = 133614 | doi = 10.1091/mbc.E02-03-0171 }}
*{{cite journal | author=He G, Gupta S, Yi M, ''et al.'' |title=ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 44044-9 |year= 2003 |pmid= 12221107 |doi= 10.1074/jbc.M208539200 }}
*{{cite journal | author=Cayrol C, Cougoule C, Wright M |title=The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1. |journal=Biochem. Biophys. Res. Commun. |volume=298 |issue= 5 |pages= 720-30 |year= 2003 |pmid= 12419313 |doi= }}
*{{cite journal | author=Yao D, Ehrlich M, Henis YI, Leof EB |title=Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4001-12 |year= 2003 |pmid= 12429842 |doi= 10.1091/mbc.02-07-0104 }}
*{{cite journal | author=Kalthoff C, Groos S, Kohl R, ''et al.'' |title=Clint: a novel clathrin-binding ENTH-domain protein at the Golgi. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4060-73 |year= 2003 |pmid= 12429846 |doi= 10.1091/mbc.E02-03-0171 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
==External links==
{{WikiDoc Sources}}
* {{UCSC gene info|AP2B1}}
{{PDB Gallery|geneid=163}}
 
 
{{gene-17-stub}}

Latest revision as of 18:05, 29 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

AP-2 complex subunit beta is a protein that in humans is encoded by the AP2B1 gene.[1][2][3]

Function

The protein encoded by this gene is one of two large chain components of the AP2 adaptor complex, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.[3]

Interactions

AP2B1 has been shown to interact with:

References

  1. ↑ Gallusser A, Kirchhausen T (Dec 1993). "The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components". The EMBO Journal. 12 (13): 5237–44. PMC 413789. PMID 8262066.
  2. ↑ Druck T, Gu Y, Prabhala G, Cannizzaro LA, Park SH, Huebner K, Keen JH (Nov 1995). "Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP". Genomics. 30 (1): 94–7. doi:10.1006/geno.1995.0016. PMID 8595912.
  3. ↑ 3.0 3.1 "Entrez Gene: AP2B1 adaptor-related protein complex 2, beta 1 subunit".
  4. ↑ 4.0 4.1 Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  5. ↑ Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS (Mar 1999). "The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis". Proceedings of the National Academy of Sciences of the United States of America. 96 (7): 3712–7. doi:10.1073/pnas.96.7.3712. PMC 22359. PMID 10097102.
  6. ↑ Kim YM, Benovic JL (Aug 2002). "Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking". The Journal of Biological Chemistry. 277 (34): 30760–8. doi:10.1074/jbc.M204528200. PMID 12070169.
  7. ↑ Cayrol C, Cougoule C, Wright M (Nov 2002). "The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1". Biochemical and Biophysical Research Communications. 298 (5): 720–30. doi:10.1016/s0006-291x(02)02522-6. PMID 12419313.
  8. ↑ He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC (Nov 2002). "ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2". The Journal of Biological Chemistry. 277 (46): 44044–9. doi:10.1074/jbc.M208539200. PMID 12221107.
  9. ↑ Yao D, Ehrlich M, Henis YI, Leof EB (Nov 2002). "Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit". Molecular Biology of the Cell. 13 (11): 4001–12. doi:10.1091/mbc.02-07-0104. PMC 133610. PMID 12429842.

Further reading

External links


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