ANTXR2

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Anthrax toxin receptor 2
PDB rendering based on 1sht.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols ANTXR2 ; CMG-2; CMG2; FLJ31074; ISH; JHF; MGC111533; MGC45856
External IDs Template:OMIM5 Template:MGI HomoloGene43236
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Anthrax toxin receptor 2, also known as ANTXR2, is a human gene.[1]


References

  1. "Entrez Gene: ANTXR2 anthrax toxin receptor 2".

Further reading

  • "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. PMID 9847074.
  • Bell SE, Mavila A, Salazar R; et al. (2002). "Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling". J. Cell. Sci. 114 (Pt 15): 2755–73. PMID 11683410.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Abrami L, Liu S, Cosson P; et al. (2003). "Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process". J. Cell Biol. 160 (3): 321–8. doi:10.1083/jcb.200211018. PMID 12551953.
  • Scobie HM, Rainey GJ, Bradley KA, Young JA (2003). "Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor". Proc. Natl. Acad. Sci. U.S.A. 100 (9): 5170–4. doi:10.1073/pnas.0431098100. PMID 12700348.
  • Dowling O, Difeo A, Ramirez MC; et al. (2003). "Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis". Am. J. Hum. Genet. 73 (4): 957–66. PMID 12973667.
  • Hanks S, Adams S, Douglas J; et al. (2003). "Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis". Am. J. Hum. Genet. 73 (4): 791–800. PMID 14508707.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Wigelsworth DJ, Krantz BA, Christensen KA; et al. (2004). "Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen". J. Biol. Chem. 279 (22): 23349–56. doi:10.1074/jbc.M401292200. PMID 15044490.
  • Lacy DB, Wigelsworth DJ, Scobie HM; et al. (2004). "Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor". Proc. Natl. Acad. Sci. U.S.A. 101 (17): 6367–72. doi:10.1073/pnas.0401506101. PMID 15079089.
  • Colland F, Jacq X, Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.
  • Santelli E, Bankston LA, Leppla SH, Liddington RC (2004). "Crystal structure of a complex between anthrax toxin and its host cell receptor". Nature. 430 (7002): 905–8. doi:10.1038/nature02763. PMID 15243628.
  • Lacy DB, Wigelsworth DJ, Melnyk RA; et al. (2004). "Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation". Proc. Natl. Acad. Sci. U.S.A. 101 (36): 13147–51. doi:10.1073/pnas.0405405101. PMID 15326297.
  • Abrami L, Lindsay M, Parton RG; et al. (2004). "Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway". J. Cell Biol. 166 (5): 645–51. doi:10.1083/jcb.200312072. PMID 15337774.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Lee JY, Tsai YM, Chao SC, Tu YF (2005). "Capillary morphogenesis gene-2 mutation in infantile systemic hyalinosis: ultrastructural study and mutation analysis in a Taiwanese infant". Clin. Exp. Dermatol. 30 (2): 176–9. doi:10.1111/j.1365-2230.2004.01698.x. PMID 15725249.
  • Abrami L, Leppla SH, van der Goot FG (2006). "Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis". J. Cell Biol. 172 (2): 309–20. doi:10.1083/jcb.200507067. PMID 16401723.
  • Gao M, Schulten K (2007). "Onset of anthrax toxin pore formation". Biophys. J. 90 (9): 3267–79. doi:10.1529/biophysj.105.079376. PMID 16473908.
  • Wei W, Lu Q, Chaudry GJ; et al. (2006). "The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin". Cell. 124 (6): 1141–54. doi:10.1016/j.cell.2005.12.045. PMID 16564009.

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