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Aldehyde dehydrogenase family 3 member B2 is an enzyme that in humans is encoded by the ALDH3B2gene.[1][2][3]
This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized.[3]
References
↑Hsu LC, Chang WC (Dec 1996). "Sequencing and expression of the human ALDH8 encoding a new member of the aldehyde dehydrogenase family". Gene. 174 (2): 319–22. doi:10.1016/0378-1119(96)00087-X. PMID8890755.
↑Hsu LC, Chang WC, Yoshida A (Jun 1997). "Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison". Gene. 189 (1): 89–94. doi:10.1016/S0378-1119(96)00839-6. PMID9161417.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.
Hsu LC, Chang WC, Lin SW, Yoshida A (1995). "Cloning and characterization of genes encoding four additional human aldehyde dehydrogenase isozymes". Adv. Exp. Med. Biol. 372: 159–68. doi:10.1007/978-1-4615-1965-2_21. PMID7484374.
