AFM (gene)

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Afamin
Identifiers
Symbols AFM ; ALB2; ALBA; ALF; MGC125338; MGC125339
External IDs Template:OMIM5 Template:MGI HomoloGene881
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Afamin, also known as AFM, is a human gene.[1]

This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.[1]

References

  1. 1.0 1.1 "Entrez Gene: AFM afamin".

Further reading

  • Noppe M, Lowenthal A, Karcher D, Gheuens J (1979). "A two-site immunoradiometric assay for the determination of alpha-albumin". J. Immunol. Methods. 27 (1): 75–81. PMID 37276.
  • Hansson E, Rönnbäck L, Lowenthal A, Noppe M (1985). "Primary cultures from defined brain areas; effects of seeding time on cell growth, astroglial content and protein synthesis". Brain Res. 353 (2): 175–85. PMID 4041902.
  • Lowenthal A, Flament-Durand J, Karcher D; et al. (1982). "Glial cells identified by anti-alpha-albumin (anti-GFA) in human pineal gland". J. Neurochem. 38 (3): 863–5. PMID 7035619.
  • Lichenstein HS, Lyons DE, Wurfel MM; et al. (1994). "Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family". J. Biol. Chem. 269 (27): 18149–54. PMID 7517938.
  • Allard D, Gilbert S, Lamontagne A; et al. (1995). "Identification of rat alpha-albumin and cDNA cloning of its human ortholog". Gene. 153 (2): 287–8. PMID 7875606.
  • Nishio H, Heiskanen M, Palotie A; et al. (1996). "Tandem arrangement of the human serum albumin multigene family in the sub-centromeric region of 4q: evolution and chromosomal direction of transcription". J. Mol. Biol. 259 (1): 113–9. doi:10.1006/jmbi.1996.0306. PMID 8648639.
  • Nishio H, Dugaiczyk A (1996). "Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene family". Proc. Natl. Acad. Sci. U.S.A. 93 (15): 7557–61. PMID 8755513.
  • Song YH, Naumova AK, Liebhaber SA, Cooke NE (1999). "Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster". Genome Res. 9 (6): 581–7. PMID 10400926.
  • Khan MA, Kumar Y, Tayyab S (2003). "Bilirubin binding properties of pigeon serum albumin and its comparison with human serum albumin". Int. J. Biol. Macromol. 30 (3–4): 171–8. PMID 12063119.
  • Voegele AF, Jerković L, Wellenzohn B; et al. (2003). "Characterization of the vitamin E-binding properties of human plasma afamin". Biochemistry. 41 (49): 14532–8. PMID 12463752.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR (2004). "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry". Proteomics. 4 (2): 454–65. doi:10.1002/pmic.200300556. PMID 14760718.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Jerkovic L, Voegele AF, Chwatal S; et al. (2005). "Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression". J. Proteome Res. 4 (3): 889–99. doi:10.1021/pr0500105. PMID 15952736.
  • Hu Y, Malone JP, Fagan AM; et al. (2006). "Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid". Mol. Cell Proteomics. 4 (12): 2000–9. doi:10.1074/mcp.M500207-MCP200. PMID 16199891.
  • Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.
  • Ramachandran P, Boontheung P, Xie Y; et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.

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