ADRM1

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Adhesion regulating molecule 1
Identifiers
Symbols ADRM1 ; GP110; MGC29536; Rpn13
External IDs Template:OMIM5 Template:MGI HomoloGene10513
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Adhesion regulating molecule 1, also known as ADRM1, is a human gene.[1]

The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.[1]

References

  1. 1.0 1.1 "Entrez Gene: ADRM1 adhesion regulating molecule 1".

Further reading

  • Shimada S, Ogawa M, Takahashi M; et al. (1994). "Molecular cloning and characterization of the complementary DNA of an M(r) 110,000 antigen expressed by human gastric carcinoma cells and upregulated by gamma-interferon". Cancer Res. 54 (14): 3831–6. PMID 8033103.
  • Simins AB, Weighardt H, Weidner KM; et al. (2000). "Functional cloning of ARM-1, an adhesion-regulating molecule upregulated in metastatic tumor cells". Clin. Exp. Metastasis. 17 (8): 641–8. PMID 10919708.
  • Deloukas P, Matthews LH, Ashurst J; et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
  • Kim JH, Lane WS, Reinberg D (2002). "Human Elongator facilitates RNA polymerase II transcription through chromatin". Proc. Natl. Acad. Sci. U.S.A. 99 (3): 1241–6. doi:10.1073/pnas.251672198. PMID 11818576.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Lamerant N, Kieda C (2005). "Adhesion properties of adhesion-regulating molecule 1 protein on endothelial cells". FEBS J. 272 (8): 1833–44. doi:10.1111/j.1742-4658.2005.04613.x. PMID 15819879.
  • Gandhi TK, Zhong J, Mathivanan S; et al. (2006). "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets". Nat. Genet. 38 (3): 285–93. doi:10.1038/ng1747. PMID 16501559.
  • Lim J, Hao T, Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
  • Jørgensen JP, Lauridsen AM, Kristensen P; et al. (2006). "Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor". J. Mol. Biol. 360 (5): 1043–52. doi:10.1016/j.jmb.2006.06.011. PMID 16815440.
  • Yao T, Song L, Xu W; et al. (2006). "Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1". Nat. Cell Biol. 8 (9): 994–1002. doi:10.1038/ncb1460. PMID 16906146.
  • Hamazaki J, Iemura S, Natsume T; et al. (2006). "A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes". EMBO J. 25 (19): 4524–36. doi:10.1038/sj.emboj.7601338. PMID 16990800.
  • Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Qiu XB, Ouyang SY, Li CJ; et al. (2007). "hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37". EMBO J. 25 (24): 5742–53. doi:10.1038/sj.emboj.7601450. PMID 17139257.

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