ACC AHA guidelines classification scheme

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview[edit]

The Class designation is used to indicate whether a therapy is recommended or not and the certainty surrounding that recommendation.

Classification of Recommendations[edit]

Class I: Benefit >>> Risk[edit]

Conditions for which there is evidence and/or general agreement that a given procedure or treatment is beneficial, useful, and effective.

Class II:[edit]

Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment.

Class IIa: Benefit >> Risk[edit]

Weight of evidence/opinion is in favor of usefulness/efficacy.

Class IIb: Benefit ≥ Risk[edit]

Usefulness/efficacy is less well established by evidence/opinion.

Class III[edit]

Conditions for which there is evidence and/or general agreement that a procedure/treatment is not useful/effective and in some cases may be harmful.

Class III: No Benefit[edit]

Is not recommended, not indicated, should not be performed/ administered/ other. Is not useful/beneficial/effective.

Class III: Harm[edit]

Potentially harmful, causes harm, associated with excess morbidity/mortality. Should not be performed/administered/other.

Use the Level of Evidence designation to indicate the strength of the data associated with that recommendation.

Level of Evidence[edit]

Level of Evidence A:[edit]

Data derived from multiple randomized clinical trials or meta-analyses of such studies.

Level of Evidence B:[edit]

Level of Evidence B-R: Data derived from one or more randomized trials or meta-analysis of such studies.
Level of Evidence B-NR: Data derived from one or more non-randomized trials or meta-analysis of such studies.

Level of Evidence C:[edit]

Level of Evidence C-LD:: Non randomized observational studies with limitations in design or execution or Metanalysis of such studies.
Level of Evidence C-EO: Consensus opinion of experts based on clinical experience.

Applying Classification of Recommendations and Level of Evidence[edit]

2016 Classification of Recommendations and Level of Evidence[edit]

Classofrecommendation.jpg Levelofevidence.jpg

2014 Classification of Recommendations and Level of Evidence[edit]

2011 AHA Classification.JPG


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