24-methylenesterol C-methyltransferase

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In enzymology, a 24-methylenesterol C-methyltransferase (EC is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 24-methylenelophenol S-adenosyl-L-homocysteine + (Z)-24-ethylidenelophenol

Thus, the two substrates of this enzyme are S-adenosyl methionine and 24-methylenelophenol, whereas its two products are S-adenosylhomocysteine and (Z)-24-ethylidenelophenol.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase. Other names in common use include SMT2, and 24-methylenelophenol C-241-methyltransferase. This enzyme participates in the biosynthesis of steroids.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Bouvier-Nave P, Husselstein T, Benveniste P (1998). "Two families of sterol methyltransferases are involved in the first and the second methylation steps of plant sterol biosynthesis". Eur. J. Biochem. 256: 88&ndash, 96. PMID 9746350.

External links

Gene Ontology (GO) codes