2,4-Dichlorobenzyl alcohol: Difference between revisions
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== Overview == | |||
'''2,4-Dichlorobenzyl alcohol''' is a mild [[antiseptic]], able to kill [[bacteria]] and [[viruses]] associated with mouth and throat [[infection]]s. It is a common ingredient in throat lozenges such as [[Strepsils]], Lorsept or [[Gorpils]]. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and [[amylmetacresol]] (600μg) has been found to deactivate [[Respiratory syncytial virus]] and [[Severe acute respiratory syndrome|SARS-Cov]], but not [[adenovirus]] or [[rhinovirus]].<ref name=Oxford>{{cite journal |author=Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A |year=2005 |title=A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV |journal=Antiviral chemistry and chemotherapy |volume=16 |pages=129–34 |pmid=15889535 |issue=2}}</ref> A [[dentifrice]] containing 10% [[sodium benzoate]] and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5–10 minutes after brushing.<ref name=Ostergaard>{{cite journal|journal=Acta Odontol Scand. |author=Ostergaard E |title=Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study. |year=1994 |volume=52 |pages=335–45 |pmid=7887143|doi=10.3109/00016359409029031|issue=6}}</ref> | |||
==References== | |||
{{reflist|2}} | |||
{{Throat preparations}} | |||
{{DEFAULTSORT:Dichlorobenzyl Alcohol, 2,4-}} | |||
[[Category:drug]] | |||
{{DEFAULTSORT:Dichlorobenzyl | |||
[[Category:Alcohols]] | [[Category:Alcohols]] | ||
[[Category:Organochlorides]] | [[Category:Organochlorides]] | ||
{{respiratory-system-drug-stub}} | |||
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Revision as of 16:44, 14 April 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils, Lorsept or Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (600μg) has been found to deactivate Respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus.[1] A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5–10 minutes after brushing.[2]
References
- ↑ Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral chemistry and chemotherapy. 16 (2): 129–34. PMID 15889535.
- ↑ Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study". Acta Odontol Scand. 52 (6): 335–45. doi:10.3109/00016359409029031. PMID 7887143.