]> 2026-07-31T16:29:25+00:00 WBR277 0 en Café au lait spots Incorrect- This newborn is showing signs of Down syndrome. Café au lait spots are associated with neurofibromatosis. High arched palate Incorrect- This newborn is showing signs of Down syndrome. High arched palates are associated with fragile X syndrome. Ambiguous genitalia Incorrect- This newborn is showing signs of Down syndrome. Ambiguous genitalia are commonly seen in CAH. Hypotonia Correct- See explanation. Club feet Incorrect- This newborn is showing signs of Down syndrome. EXPLANATION: The most common finding in a newborn with Down syndrome is hypotonia. Other common findings include single palmar crease, flat facial profile, macroglossia, and wide space between the first and second toes. Hypotonia in the newborn period should prompt close evaluation and follow-up. EDUCATIONAL OBJECTIVE: The most common finding in a newborn with Down syndrome is hypotonia which should prompt close evaluation and follow-up.<br/> '''Educational Objective:''' <br/> '''References:''' Community Medical Health Center Primary Care Office Physician is called to see a newborn in the nursery because the nurse is concerned that the baby have single crease in the palm of the hand, small ears, small mouth, upward slanting eyes, wide space between the first and second toes, short hands with short fingers. Which of the following sign is most likely associated in this newborn? D Pediatrics 2020-10-28T02:59:25Z 2459150.6245949 WBR277