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		<swivt:creationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-07-31T09:40:56+00:00</swivt:creationDate>
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		<rdfs:label>WBR258</rdfs:label>
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		<property:AnswerA rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Rupture of a papillary muscle due to an ischemic event</property:AnswerA>
		<property:AnswerAExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">This answer would relate an ischemic event.</property:AnswerAExp>
		<property:AnswerB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Myxomatous degeneration of a heart valve</property:AnswerB>
		<property:AnswerBExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Correct answer.  Mitral valve prolapse is due to  of myxomatous degeneration of the mitral valve leading to a  floppy mitral valve.</property:AnswerBExp>
		<property:AnswerC rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Congenital bicuspid anomaly of valvular leaflets</property:AnswerC>
		<property:AnswerCExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">usually an abnormality of the aortic valve.</property:AnswerCExp>
		<property:AnswerD rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Lipid deposition and plaque formation in the arterial walls</property:AnswerD>
		<property:AnswerDExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">This answer relates to an atherosclerotic process</property:AnswerDExp>
		<property:AnswerE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Rheumatic heart disease</property:AnswerE>
		<property:AnswerEExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Rheumatic fever is an inflammatory disease that occurs following a Streptococcus pyogenes infection, such as streptococcal pharyngitis. Chronic rheumatic heart disease (RHD) is characterized by repeated inflammation with fibrinous resolution. It presents with polyarthritis, Carditis, subcutaneous nodules, erythema marginatum, fever, leukocytosis, ECG may show features of heart block, such as a prolonged PR interval.</property:AnswerEExp>
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		<property:Explanation rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mitral valve prolapse (aka primary form of myxomatous degeneration of the mitral valve aka floppy mitral valve syndrome) is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole. Upon auscultation of an individual with mitral valve prolapse, a mid-systolic click, followed by a late systolic murmur heard best at the apex is common.  Echocardiography is the most useful method of diagnosing a prolapsed mitral valve. Two- and three-dimensional echocardiography are particularly valuable as they allow visualization of the mitral leaflets relative to the mitral annulus. This allows measurement of the leaflet thickness and their displacement relative to the annulus. Thickening of the mitral leaflets &gt;5 mm and leaflet displacement &gt;2 mm indicates classic mitral valve prolapse.&lt;br/&gt;
'''Educational Objective:''' &lt;br/&gt;
'''References:'''</property:Explanation>
		<property:MainCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Internal medicine</property:MainCategory>
		<property:PageAuthor rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mahmoud Sakr M.D.</property:PageAuthor>
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		<property:Prompt rdf:datatype="http://www.w3.org/2001/XMLSchema#string">43 y/o female presents to her primary care physician for routine health examination.  She denies any complaints and walks 2 miles 3 times a week.  Initial evaluation reveals a Blood pressure is 127/77 mm Hg, Pulse is 82 /min, RR 14, oxygen saturation of 99% on room air.  Physical examination is unremarkable except for a midsystolic click on cardiac auscultation. Which of the following mechanisms is likely responsible for this physical finding;</property:Prompt>
		<property:RightAnswer rdf:datatype="http://www.w3.org/2001/XMLSchema#string">B</property:RightAnswer>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cardiovascular</property:SubCategory>
		<swivt:wikiPageModificationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-10-28T02:55:18Z</swivt:wikiPageModificationDate>
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