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	<owl:Ontology rdf:about="https://www.wikidoc.org/index.php/Special:ExportRDF/WBR0962">
		<swivt:creationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-07-31T09:41:31+00:00</swivt:creationDate>
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		<rdf:type rdf:resource="https://www.wikidoc.org/index.php/Special:URIResolver/Category-3AWBRQuestion"/>
		<rdf:type rdf:resource="https://www.wikidoc.org/index.php/Special:URIResolver/Category-3APages_using_duplicate_arguments_in_template_calls"/>
		<rdfs:label>WBR0962</rdfs:label>
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		<property:AnswerA rdf:datatype="http://www.w3.org/2001/XMLSchema#string">I.V platelet transfusion</property:AnswerA>
		<property:AnswerAExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">''' Incorrect ''' : Platelet transfusion is not normally recommended and is usually unsuccessful in raising a patient's platelet count.  This is because the underlying autoimmune mechanism that destroyed the patient's platelets to begin with will also destroy donor platelets.  An exception to this rule is when a patient is bleeding profusely, when transfusion of platelets can quickly form a platelet plug to stop bleeding, a life-threatening hemorrhage.  Intravenous immunoglobulin administration, with the platelet transfusion, may improve their survival.</property:AnswerAExp>
		<property:AnswerB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">I.V immunoglobulin</property:AnswerB>
		<property:AnswerBExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">''' Incorrect ''' : The platelet count can be temporarily supported by the use of intravenous immune globulin (IVIG) or by anti-Rh(D) (Rho(D) immune globulin, anti-D, WinRho) in patients whose red cells are Rh(D) positive and who have not had a splenectomy.  Both of these agents increase the platelet count in most patients with ITP, including patients who have not responded to corticosteroids, within several days, with an effect that may last for several weeks</property:AnswerBExp>
		<property:AnswerC rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Splenectomy</property:AnswerC>
		<property:AnswerD rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Observation and follow-up</property:AnswerD>
		<property:AnswerDExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">''' Correct ''' : Avoid unnecessary treatment of asymptomatic patients with mild to moderate thrombocytopenia (ie, a platelet count greater than 30,000/microL).</property:AnswerDExp>
		<property:AnswerE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">I.V glucocorticoids</property:AnswerE>
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		<property:ExamType rdf:resource="&wiki;USMLE_Step_3"/>
		<property:MainCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Primary Care Office</property:MainCategory>
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		<property:Prompt rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A 24 year old male comes to your office for regular health check up as he is joining a new job.  He has no symptoms and his past history is insignificant.   His family history is positive for hypertension in both his parents.  He is sexually active and uses contraception.  His vitals are temperature: 36.7 C, blood pressure: 120/80 mmHg, pulse: 90/min and respirations: 15/min.  All system examinations are normal.  His laboratory values are as follows : 

Blood glucose : 98 g/dl
Hb : 13 g/dl
RBC’s : 2.5 million/cmm
WBC’s : 6000/cmm
Platelets : 35,000/cmm
Neutrophils : 60 %
Lymphocytes : 32 %
MCV : 85 fl
ESR : 15mm/hr
PT : 13 sec (N 11-15 sec)
APTT : 30 sec (N 25-40 sec)
BT : 9 min (N 2-7 min)
Serum creatinine : 1.2 mg/dl
Serum calcium : 9 g/dl

Which of the following is the best next step in the management of this patient?</property:Prompt>
		<property:RightAnswer rdf:datatype="http://www.w3.org/2001/XMLSchema#string">D</property:RightAnswer>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hematology</property:SubCategory>
		<property:WBRKeyword rdf:resource="&wiki;Idiopathic_thrombocytopenic_purpura"/>
		<swivt:wikiPageModificationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-10-28T02:12:16Z</swivt:wikiPageModificationDate>
		<property:Modification_date-23aux rdf:datatype="http://www.w3.org/2001/XMLSchema#double">2459150.5918519</property:Modification_date-23aux>
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