]> 2026-07-31T09:41:25+00:00 WBR0862 0 en Small dark blue neuroendocrine cells This pattern is typical of SCLC. Keratin pearls and retracted cells This pattern is seen in squamous cell carcinoma. Paraneoplastic syndromes associated with squamous cell carcinoma include PTHrP hypercalcemia. Pleomorphic giant cells This pattern is typical of large cell lung carcinoma. Granuloma formation with caseating necrosis This pattern is usually diagnostic of active tubeculosis. Granuloma formation without caseating necrosis This pattern is usually seen in sarcoidosis and some cases of tuberculosis. Pathology A 56-year-old man presents to the neurology clinic for 3 weeks of upper and lower extremity weakness. The patient explains that he works as a plumber and that his everyday chores have become much harder since he has started to notice this weakness. Despite this, he has noticed a pattern that allows him to overcome it. He reports that the longer he is at rest, the weaker he feels, and as soon as he exerts himself he restores a lot of the strength in his extremities. Physical exam reveals 2/5 strength in all four extremities, bilateral eyelid ptosis, and absent deep tendon reflexes. With a certain diagnostic suspicion, the physician orders a chest CT that reveals a 2.5 cm mass adjacent to the left stem bronchus. Biopsy of the mass is likely to reveal which of the following findings? A Pulmonology 2020-10-28T01:54:58Z 2459150.579838 WBR0862