]> 2026-07-31T09:40:49+00:00 WBR0739 0 en A LTB4 is a neutrophil chemotactic agent. It does not play a major role in reducing platelet aggregation. B LTC4 and LTD4 are pro-inflammatory agents that play a role in bronchoconstriction. C Prostacyclin is a major inhibitor of platelet aggregation. D Prostaglandins increase uterine tone. Prostaglandins may be administered to pregnant patients to induce labor. Prostaglandins also decrease vascular and bronchial tone. E Thromboxane A2 has an effect that opposes that of prostacyclin. It increases platelet aggregation and plays a role in worsening atherosclerosis. The medication described must have properties that reduce platelet aggregation to counteract the process of myocardial infarction. Prostacyclin (PGI2) is a potent inhibitor of platelet aggregation. Also, it plays a role in promoting vasodilation and bronchodilation, along with decreasing uterine tone. Since the drug increases compounds that inhibit platelet aggregation, the new compound must increase PGI2 levels, and thus promote inhibition of platelet aggregation.<br/> '''Educational Objective:''' Prostacyclin inhibits platelet aggregation.<br/> '''References:''' First Aid 2014 page 439 Physiology C Cardiology 2020-10-28T01:32:10Z 2459150.5640046 WBR0739