]> 2026-07-31T09:41:37+00:00 WBR0726 0 en Ramipril Ramipril is an ACE-inhibitor that has several indications, such as hypertension, diabetic nephropathy, and cardiac left ventricular dysfunction. Gynecomastia is not a typical adverse effect of ACE-inhibitors. Furosemide Furosemide is a loop diuretic indicated for symptomatic congestive heart failure. Gynecomastia is not a typical adverse effect of loop diuretics. Cimetidine Cimetidine is an H2 receptor blocker indicated for GERD. Gynecomastia is a known adverse effect of cimetidine. Omeprazole Omeprazole is a proton pump inhibitor indicated for GERD. Gynecomastia is not a typical adverse effect of PPI. Fenofibrate Fenofibrate is indicated for dyslipidemia, especially hypertriglyceridemia. Gynecomastia is not a typical adverse effect of fenofibrate therapy. The patient is presenting with gynecomastia. Use of several medications are associated with gynecomastia. Knowing these medications is important for the USMLE. The following is a list of medications and conditions that are associated with gynecomastia: <br> 1- Medications: Spironolactone, digitalis, cimetidine, ketoconazole, dopamine, anti-psychotic drugs<br> 2- Substances: Alcohol, heroin, marijuana <br> 3- Diseases: Klinefelter syndrome, cirrhosis, testicular tumors<br> 4- Physiological conditions: Puberty, old age, estogen<br/> '''Educational Objective:''' Gynecomastia is an adverse effect of cimetidine.<br/> '''References:''' First Aid 2014 page 586 Pharmacology A 62-year-old man presents to the physician's office for bilateral breast enlargement. He has a past medical history significant for coronary artery disease, status-post coronary artery bypass graft (CABG), advanced congestive heart failure, gastroesophageal reflux disease (GERD), dyslipidemia, and hypertension. He is currently taking aspirin, ramipril, metoprolol, furosemide, omeprazole, cimetidine, simvastatin, and fenofibrate. He denies smoking, alcohol intake, or use of illicit drugs. The physician suspects his condition is an adverse effect of a medication he is taking. Which of the patient's medications is most likely responsible for his condition? C Gastrointestinal 2020-10-28T01:30:00Z 2459150.5625 WBR0726