]> 2026-07-31T16:29:01+00:00 WBR0459 0 en Acute pancreatitis Acute pancreatitis may be caused by hypertriglyceridemia, not with fenofibrate therapy per se. Acute cholecystitis Gallbladder stone formation and subsequent acute cholecystitis have been associated with fibrate therapy, especially clofibrate. Pulmonary embolism Clofibrate therapy is not commonly associated with an increased risk of pulmonary embolism. Pneumonia Clofibrate therapy is not commonly associated with an increased risk of pneumonia. Myocardial infarction Hypercholesterolemia predisposes patients to myocardial infarction through atherosclerotic plaque formation. Fibrate therapy may reduce cholesterol levels, but its most pronounced effect is the reduction of triglycerides. Statins are more beneficial in the treatment of hypercholesterolemia. Pharmacology A 56 year old patient presents to his physician’s office for his annual check-up. Appropriate work-up reveals that the patient has elevated levels of triglycerides. The physician decides to initiate therapy with clofibrate. Several weeks later, the patient presents to the emergency department with epigastric pain. The physician in the emergency department suspects the patient’s symptoms are associated with the clofibrate therapy. What is the most likely diagnosis of this patient’s epigastric pain? B Gastrointestinal Vascular 2020-10-28T00:38:34Z 2459150.5267824 WBR0459