]> 2026-07-31T16:29:05+00:00 WBR0423 0 en Vitamin B1 Vitamin B1 is a cofactor of pyruvate dehydrogenase. Vitamin C Vitamin C is a cofactor for dopamine beta-hydroxylase. Vitamin B3 Vitamin B12 is a cofactor for homocysteine methyltransferase and methylmalonyl-CoA mutase. Vitamin K Vitamin K is a cofactor for the carboxylase enzyme that catalyzes carboxylation of glutamic acid residues. Vitamin B6 Vitamin B6 is required for the synthesis of cystathionine, heme, GABA, dopamine, niacin, and histamine. It is not a cofactor of pyruvate dehydrogenase. Biochemistry A 3-month-old boy is brought by his mother to the physician's office for hypotonia. The mother was recently told that her son's disease may be caused by an enzyme deficiency. Upon further work-up, the physician explains that the deficient enzyme is normally responsible to convert pyruvate to acetyl CoA, and the patient is required to be on a ketogenic diet. Which of the following cofactors is required for the normal functioning of the enzyme deficient in this patient? A Neurology 2020-10-28T00:30:48Z 2459150.5213889 WBR0423