]> 2026-07-31T11:52:04+00:00 WBR0320 0 en A "A" does not correspond to HGPRT. It corresponds to AMP deaminase. B "B" corresponds to HGPRT. HGPRT deficiency results in Lesch-Nyhan syndrome. C "C" corresponds to adenosine phosphoribosyltransferase (APRT). APRT deficiency is an extremely rare disease associated with increased risk of kidney stones. D "D" corresponds to adenosine deaminase (ADA). Deficiency of ADA is associated with severe combined immunodeficiency (SCID). E "E" corresponds to adenosine kinase not HGPRT. Severe developmental abnormalities and early postnatal death have been documented in knockout animal models. You are not required to know this information for the USMLE Step 1. Biochemistry B Neurology 2020-10-28T00:10:47Z 2459150.5074884 WBR0320