]> 2026-07-31T11:51:14+00:00 WBR0296 0 en Brain tumor that arises from the cells that secrete cerebrospinal fluid (CSF) Ependymoma is a brain tumor that arises from the ependymal cells, which are cells that secrete CSF. Ependymoma and other brain tumors are a cause of syringomyelia, but they are not the most common cause. Hindbrain malformation characterized by the abnormal downward herniation of the cerebellar tonsils below the foramen magnum Syringomyelia is most commonly associated with Chiari I malformation (CMI), a hindbrain malformation characterized by the abnormal downward herniation of the cerebellar tonsils below the foramen magnum. Neural tube defect characterized by the protrusion of the spinal cord and membranes through a defective vertebral column Myelomeningocele is a neural tube defect that is characterized by the protrusion of the spinal cord and membranes through a defective vertebral column. It involves multiple tissue layers, including the spinal cord, dura, soft tissue, and skin. Chiari II malformation is a congenital deformity of the posterior fossa and the spine that is characterized by an elongated small cerebellum, a small posterior fossa, and a caudal shift of the brainstem due to the disproportionate and rapid development of the brain tissue in the dural posterior fossa. Unlike Chiari I malformation, Chiari II malformation usually manifests early in childhood or even during the neonatal period and is almost always associated with myelomeningocele and hydrocephalus. Congenital deformity of the posterior fossa and the spine caused by the disproportionate and rapid development of the brain tissue in the dural posterior fossa Chiari II malformation is a congenital deformity of the posterior fossa and the spine that is characterized by an elongated small cerebellum, a small posterior fossa, and a caudal shift of the brainstem due to the disproportionate and rapid development of the brain tissue in the dural posterior fossa. Unlike Chiari I malformation, Chiari II malformation usually manifests early in childhood or even during the neonatal period and is almost always associated with myelomeningocele and hydrocephalus. Agenesis of the cerebellar vermis and cystic enlargement of the fourth ventricle Dandy-Walker syndrome (DWS) is the agenesis of the cerebellar vermis and cystic enlargement of the fourth ventricle. DWS is classically associated with hydrocephalus and spina bifida. Embryology A 32-year-old man presents to the physician’s office with complaints of progressive numbness of the arms, weakness, and hiccups. His past medical history is unremarkable, and the patient denies intake of any medications. Physical examination is remarkable for bilateral loss of pain and temperature sensations over the shoulders and the upper extremities in a cape-like distribution. The physician also notes decreased sensation and a motor strength of 3/5 in the upper extremities. MRI of the brain and the neck is performed and demonstrates a dilated fluid-filled cavity in the spinal cord. Which of the following diseases is most commonly associated with this patient's condition? B Neurology 2020-10-28T00:05:54Z 2459150.5040972 WBR0296