]> 2026-07-31T09:41:02+00:00 WBR0293 0 en X-linked recessive disorder X-linked dominant disorder Hypophosphatemic rickets is an example of an X-linked dominant disorder. Autosomal dominant disorder Huntington's disease, hereditary hemorrhagic telangiectasia, Marfan syndrome, neurofibromatosis types 1 and 2, tuberous sclerosis, and von-Hippel Lindau are all examples of autosomal dominant disorders. Autosomal recessive disorder Albinism, cystic fibrosis, Kartagener syndrome, sickle cell disease, and phenylketonuria are all examples of autosomal recessive disorders. Mitochondrial inheritance MERRF syndrome (Myoclonic Epilepsy with Ragged Red Fibers) and MELAS (Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) are 2 examples of diseases with mitochondrial inheritance. Genetics A 4-month old boy is brought to the physician's office for psychomotor delay. The mother explains that the patient cannot sit or support his head. She states that his symptoms began when she noticed orange crystals in his diapers 5 weeks ago and have been progressively worsening. The boy has no significant past medical history and had a normal neonatal course. Laboratory findings demonstrate megaloblastic anemia, normal concentrations of vitamin B12 and folate, and increased concentrations of uric acid in blood and in urine. What type of inheritance pattern is associated with this patient's condition? A General Principles 2020-10-28T00:04:48Z 2459150.5033333 WBR0293