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	<owl:Ontology rdf:about="https://www.wikidoc.org/index.php/Special:ExportRDF/WBR0269">
		<swivt:creationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-07-31T11:51:56+00:00</swivt:creationDate>
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		<rdfs:label>WBR0269</rdfs:label>
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		<property:AnswerA rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sputum cultures for mycobacterium tuberculosis</property:AnswerA>
		<property:AnswerB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Drug susceptibility testing</property:AnswerB>
		<property:AnswerBExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Incorrect'''-A drug susceptibility testing is only a reliable lab test done before initiating treatment for the multi drug resistant strain.  It is not useful in diagnosing the cause of hypotension in this patient.</property:AnswerBExp>
		<property:AnswerC rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Early morning serum cortisol and cosyntropin stimulation</property:AnswerC>
		<property:AnswerCExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Correct'''-This patient’s hypotension along with symptoms of weakness, fatigue, and weight loss in combination extensor hyperpigmentation are all consistent with Addisons disease.  Tuberculosis can involve the adrenal glands as an extra pulmonary manifestation and result in adrenal insufficiency.  Measurement of serum cortisol baseline and then stimulation with ACTH will confirm the clinical suspicion.  Cortisol response is measured after cosyntropin is given intramuscularly or intravenously.  The ACTH stimulation test is used to determine the adrenal reserve capacity for steroid production.</property:AnswerCExp>
		<property:AnswerD rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Blood culture</property:AnswerD>
		<property:AnswerDExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Incorrect'''-Blood culture is not useful as the patients temperature is normal and septic shock is not suspected.</property:AnswerDExp>
		<property:AnswerE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chest X ray</property:AnswerE>
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		<property:MainCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Community Medical Health Center</property:MainCategory>
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		<property:PageAuthor rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Vendhan Ramanujam</property:PageAuthor>
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		<property:Prompt rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A 46 year old alcoholic male is being treated for tuberculosis, but he has not been compliant with his medications.  He comes to his physicians office and complains of increasing weakness, fatigue and febrile episodes on and off over the past one week.  He appears to have lost weight.  His temperature is 99.6 F (35.6 C), pulse is 96/minute and blood pressure is 80/50 mmHg.  There are some pigmentation over the elbows. Cardiac exam is normal.  There is a possibility that he has developed a multi drug resistant strain of tuberculosis.  The next best step in evaluation of the patients low blood pressure will be</property:Prompt>
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		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Endocrine</property:SubCategory>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Infectious Disease</property:SubCategory>
		<swivt:wikiPageModificationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-10-28T00:00:51Z</swivt:wikiPageModificationDate>
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