]> 2026-07-31T11:52:04+00:00 WBR0142 0 en Papillary carcinoma of the thyroid This patient has Hashimoto’s thyroiditis, which does not typically increase the risk of developing papillary carcinoma of the thyroid. Papillary carcinoma of the thyroid is the most common thyroid cancer. It may be associated with ''BRAF V600E'' mutations that may now be treated with vemurafenib. Other genetic alterations involve ''NRAS'' point mutation and RET translocation. Follicular carcinoma of the thyroid Hashimoto's thyroiditis does not usually increase the risk of developing follicular carcinoma of the thyroid. Follicular thyroid carcinoma is associated with a good prognosis and may be associated with ''RAS'' mutations. Medullary carcinoma of the thyroid Non-Hodgkin's lymphoma Anaplastic carcinoma of the thyroid Hashimoto's thyroiditis does not usually increase the risk of developing anaplastic carcinoma of the thyroid. These tumors carry a poor prognosis and tend to occur in older patients. Pathology A 27-year-old woman with no past medical history presents to her primary care physician for generalized fatigue and difficulty concentrating for the past three months. She has been smoking half a pack of cigarettes each day for the past 8 years and drinks alcohol occasionally. Upon review of systems, she reports hair loss, dry skin, constipation, and cold intolerance. Serology for anti-thyroid peroxidase antibodies is positive. This patient is at increased risk of developing which of the following malignancies? D Endocrine 2020-10-27T23:28:02Z 2459150.4778009 WBR0142