]> 2026-07-31T09:40:15+00:00 WBR0096 0 en The disease follows autosomal recessive inheritance The disease is associated with subcutaneous deposits The disease is associated with hepatomegaly The disease is associated with increased chylomicrons The disease is caused by gain-of-function mutations in HMG-CoA reductase Genetics A 20-year-old man presents to the emergency department (ED) with an acute severe substernal chest pain at rest. The patient denies recent physical trauma or illicit drug use. His past medical history is unremarkable. His father died of cardiovascular disease at young age, and his mother was recently diagnosed with lung cancer. In the ED, the patient is afebrile, blood pressure is 175/90 mmHg, heart rate is 110/min, and respiratory rate is 22/min. His ECG shows ST-segment elevation in leads V1-V4. Laboratory values show elevated troponin, LDL-cholesterol of 840 mg/dL, and HDL-cholesterol of 30 mg/dL. Which of the following is most likely true of this patient’s condition? B Cardiology 2020-10-27T23:20:08Z 2459150.4723148 WBR0096