WBR0487

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Author [[PageAuthor::Rim Halaby, M.D. [1]]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Pathophysiology
Sub Category SubCategory::Oncology
Prompt [[Prompt::A 36 year old woman presents to her primary care physician with complaints of fatigue, loss of energy and decreased exercise tolerance. She had noticed she wasn't feeling completely normal for the past 3 to 4 months but points out the past 3 weeks have been very unusual for her. Physical exam is mostly unremarkable except for minor splenomegaly. Lab ordered are shown below. Peripheral blood smear stains very low to absent for leukocyte alkaline phosphatase. Which of the following treatments is most likely to be considered in this patient?

Hb = 9
Hct = 26.8
MCV = 82
Plt = 120000
WBCs = 24000
%N = 96
%L = 2
]]

Answer A AnswerA::Hydroxyurea
Answer A Explanation AnswerAExp::
Answer B AnswerB::Cytarabine
Answer B Explanation AnswerBExp::
Answer C AnswerC::Methotrexate
Answer C Explanation AnswerCExp::
Answer D AnswerD::Cisplatin
Answer D Explanation AnswerDExp::
Answer E AnswerE::Imatinib
Answer E Explanation AnswerEExp::
Right Answer RightAnswer::E
Explanation [[Explanation::

Educational Objective:
References: ]]

Approved Approved::No
Keyword WBRKeyword::CML, WBRKeyword::Chronic myelogenous leukemia, WBRKeyword::Imatinib, WBRKeyword::bcr-abl
Linked Question Linked::
Order in Linked Questions LinkedOrder::