Achalasia history and symptoms

Revision as of 00:29, 16 July 2013 by Rim Halaby (talk | contribs)
Jump to navigation Jump to search

Achalasia Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Achalasia from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Achalasia history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Achalasia history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Achalasia history and symptoms

CDC on Achalasia history and symptoms

Achalasia history and symptoms in the news

Blogs on Achalasia history and symptoms

Directions to Hospitals Treating Achalasia

Risk calculators and risk factors for Achalasia history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief:Rim Halaby

Overview

The main symptoms of achalasia are dysphagia that is described as difficulty in swallowing, regurgitation of undigested food, retrosternal chest pain and weight loss[1]. Dysphagia involves both fluids and solids and progressively worsens over time. The chest pain experienced, also known as cardiospasm and non-cardiac chest pain can often be mistaken for a heart attack. Food and liquid, including saliva, can be retained in the esophagus and may be aspirated into the lungs. Some people may also experience coughing when lying in a horizontal position.

History and Symptoms

History

Achalasia is a rare swallowing disorder. It most commonly starts as difficulty swallowing both liquids and solids and becomes worse with time. The specificity of dysphagia for liquids is relatively high, although it can be seen in other diseases such as progressive systemic sclerosis. 40 % of patients describe weight loss, regurgitation, chest pain and heartburn. Due to the slowly progressive nature of the disease, many patients have symptoms for years prior to seeking medical attention. Patients often adopt certain behaviors to enhance esophageal emptying such as lifting the neck or throwing their shoulders back. The incidence of esophageal cancer is controversial in patients with achalasia. Some Swedish studies report an increased incidence, and suggest routine surveillance esophago-gastroduodenoscopy (EGD). This has not been shown to be the case in the U.S.A., and current recommendations do not include routine EGD. There is no cure for achalasia; however, several therapeutic methods are used to relieve the symptoms.

Symptoms

  • Dysphagia for solids and liquids is the most common feature, being seen in 91 % and 85% respectively
  • Regurgitation of undigested food
  • Cough mainly when lying down
  • Weight loss due to inadequate nutrient intake
  • Non-cardiac chest pain that may radiate to the back, jaw, neck, and arms
  • Heartburn
  • Hiccup
  • Difficulty belching is seen in 85 % of patients and likely results from failure of the UES to relax

References

  1. Dughera L, Cassolino P, Cisarò F, Chiaverina M (2008). "Achalasia". Minerva Gastroenterol Dietol. 54 (3): 277–85. PMID 18614976.