PIK3C3

Phosphoinositide-3-kinase, class 3
Identifiers
Symbols	PIK3C3 ; MGC61518; Vps34
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1986
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE PIK3C3 204297 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Phosphoinositide-3-kinase, class 3, also known as PIK3C3, is a human gene.

Further reading

• Lee C, Liu QH, Tomkowicz B; et al. (2004). "Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways". J. Leukoc. Biol. 74 (5): 676–82. doi:10.1189/jlb.0503206. PMID 12960231.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vogel LB, Fujita DJ (1994). "The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes". Mol. Cell. Biol. 13 (12): 7408–17. PMID 7504174.
• Volinia S, Dhand R, Vanhaesebroeck B; et al. (1995). "A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system". EMBO J. 14 (14): 3339–48. PMID 7628435.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Milani D, Mazzoni M, Borgatti P; et al. (1996). "Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells". J. Biol. Chem. 271 (38): 22961–4. PMID 8798481.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Panaretou C, Domin J, Cockcroft S, Waterfield MD (1997). "Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex". J. Biol. Chem. 272 (4): 2477–85. PMID 8999962.CS1 maint: Multiple names: authors list (link)
• Mazerolles F, Barbat C, Fischer A (1997). "Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity". Eur. J. Immunol. 27 (9): 2457–65. PMID 9341793.CS1 maint: Multiple names: authors list (link)
• Borgatti P, Zauli G, Colamussi ML; et al. (1998). "Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". Eur. J. Immunol. 27 (11): 2805–11. PMID 9394803.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Borgatti P, Zauli G, Cantley LC, Capitani S (1998). "Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells". Biochem. Biophys. Res. Commun. 242 (2): 332–7. PMID 9446795.CS1 maint: Multiple names: authors list (link)
• Milani D, Mazzoni M, Zauli G; et al. (1998). "HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells". AIDS. 12 (11): 1275–84. PMID 9708406.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jauliac S, Mazerolles F, Jabado N; et al. (1998). "Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity". Eur. J. Immunol. 28 (10): 3183–91. PMID 9808187.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Park IW, Wang JF, Groopman JE (2001). "HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes". Blood. 97 (2): 352–8. PMID 11154208.CS1 maint: Multiple names: authors list (link)
• Zauli G, Milani D, Mirandola P; et al. (2001). "HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway". FASEB J. 15 (2): 483–91. doi:10.1096/fj.00-0354com. PMID 11156964.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Deregibus MC, Cantaluppi V, Doublier S; et al. (2002). "HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells". J. Biol. Chem. 277 (28): 25195–202. doi:10.1074/jbc.M200921200. PMID 11994280.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cook JA, August A, Henderson AJ (2002). "Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism". J. Immunol. 169 (1): 254–60. PMID 12077252.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• François F, Klotman ME (2003). "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages". J. Virol. 77 (4): 2539–49. PMID 12551992.
• Vergne I, Chua J, Deretic V (2003). "Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade". J. Exp. Med. 198 (4): 653–9. doi:10.1084/jem.20030527. PMID 12925680.CS1 maint: Multiple names: authors list (link)
• Khan NA, Di Cello F, Nath A, Kim KS (2004). "Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells". J. Neurovirol. 9 (6): 584–93. PMID 14602571.CS1 maint: Multiple names: authors list (link)