Exosome component 2

Exosome component 2
File:PBB Protein EXOSC2 image.jpg PDB rendering based on 2nn6.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2nn6​
Identifiers
Symbols	EXOSC2 ; RRP4; Rrp4p; hRrp4p; p7
External IDs	Template:OMIM5 Template:MGI HomoloGene: 6095
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Exosome component 2, also known as EXOSC2, is a human gene.

Further reading

• Adams MD, Dubnick M, Kerlavage AR; et al. (1992). "Sequence identification of 2,375 human brain genes". Nature. 355 (6361): 632–4. doi:10.1038/355632a0. PMID 1538749.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Morris CM, Heisterkamp N, Groffen J, Fitzgerald PH (1991). "Entire ABL gene is joined with 5'-BCR in some patients with Philadelphia-positive leukemia". Blood. 78 (4): 1078–84. PMID 1868241.CS1 maint: Multiple names: authors list (link)
• Zhu QS, Heisterkamp N, Groffen J (1990). "Characterization of the human ABL promoter regions". Oncogene. 5 (6): 885–91. PMID 2163052.CS1 maint: Multiple names: authors list (link)
• Soekarman D, van Denderen J, Hoefsloot L; et al. (1990). "A novel variant of the bcr-abl fusion product in Philadelphia chromosome-positive acute lymphoblastic leukemia". Leukemia. 4 (6): 397–403. PMID 2193202.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen SJ, Chen Z, Font MP; et al. (1989). "Structural alterations of the BCR and ABL genes in Ph1 positive acute leukemias with rearrangements in the BCR gene first intron: further evidence implicating Alu sequences in the chromosome translocation". Nucleic Acids Res. 17 (19): 7631–42. PMID 2678002.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Heisterkamp N, Stam K, Groffen J; et al. (1985). "Structural organization of the bcr gene and its role in the Ph' translocation". Nature. 315 (6022): 758–61. PMID 2989703.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shtivelman E, Lifshitz B, Gale RP; et al. (1986). "Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene". Cell. 47 (2): 277–84. PMID 3021337.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Grosveld G, Verwoerd T, van Agthoven T; et al. (1987). "The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript". Mol. Cell. Biol. 6 (2): 607–16. PMID 3023859.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bernards A, Rubin CM, Westbrook CA; et al. (1987). "The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia". Mol. Cell. Biol. 7 (9): 3231–6. PMID 3313010.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Groffen J, Heisterkamp N, Grosveld F; et al. (1982). "Isolation of human oncogene sequences (v-fes homolog) from a cosmid library". Science. 216 (4550): 1136–8. PMID 6281890.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Heisterkamp N, Groffen J, Stephenson JR (1983). "The human v-abl cellular homologue". J. Mol. Appl. Genet. 2 (1): 57–68. PMID 6302194.CS1 maint: Multiple names: authors list (link)
• Heisterkamp N, Stephenson JR, Groffen J; et al. (1984). "Localization of the c-ab1 oncogene adjacent to a translocation break point in chronic myelocytic leukaemia". Nature. 306 (5940): 239–42. PMID 6316147.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Groffen J, Stephenson JR, Heisterkamp N; et al. (1984). "Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22". Cell. 36 (1): 93–9. PMID 6319012.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chissoe SL, Bodenteich A, Wang YF; et al. (1995). "Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation". Genomics. 27 (1): 67–82. PMID 7665185.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Litz CE, McClure JS, Copenhaver CM, Brunning RD (1993). "Duplication of small segments within the major breakpoint cluster region in chronic myelogenous leukemia". Blood. 81 (6): 1567–72. PMID 8453102.CS1 maint: Multiple names: authors list (link)
• Mitchell P, Petfalski E, Tollervey D (1996). "The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism". Genes Dev. 10 (4): 502–13. PMID 8600032.CS1 maint: Multiple names: authors list (link)
• Mitchell P, Petfalski E, Shevchenko A; et al. (1997). "The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases". Cell. 91 (4): 457–66. PMID 9390555.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Allmang C, Petfalski E, Podtelejnikov A; et al. (1999). "The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases". Genes Dev. 13 (16): 2148–58. PMID 10465791.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brouwer R, Allmang C, Raijmakers R; et al. (2001). "Three novel components of the human exosome". J. Biol. Chem. 276 (9): 6177–84. doi:10.1074/jbc.M007603200. PMID 11110791.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen CY, Gherzi R, Ong SE; et al. (2002). "AU binding proteins recruit the exosome to degrade ARE-containing mRNAs". Cell. 107 (4): 451–64. PMID 11719186.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)