CA10

Carbonic anhydrase X
Identifiers
Symbols	CA10 ; CA-RPX; CARPX; HUCEP-15
External IDs	Template:OMIM5 Template:MGI HomoloGene: 23201
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Carbonic anhydrase X, also known as CA10, is a human gene.

This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.

Further reading

• Supuran CT, Scozzafava A, Casini A (2003). "Carbonic anhydrase inhibitors". Med Res Rev. 23 (2): 146–89. doi:10.1002/med.10025. PMID 12500287.CS1 maint: Multiple names: authors list (link)
• Supuran CT, Vullo D, Manole G; et al. (2005). "Designing of novel carbonic anhydrase inhibitors and activators". Curr Med Chem Cardiovasc Hematol Agents. 2 (1): 49–68. PMID 15328829.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pastorekova S, Parkkila S, Pastorek J, Supuran CT (2004). "Carbonic anhydrases: current state of the art, therapeutic applications and future prospects". J Enzyme Inhib Med Chem. 19 (3): 199–229. PMID 15499993.CS1 maint: Multiple names: authors list (link)
• Hewett-Emmett D, Tashian RE (1996). "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families". Mol. Phylogenet. Evol. 5 (1): 50–77. doi:10.1006/mpev.1996.0006. PMID 8673298.
• Kleiderlein JJ, Nisson PE, Jessee J; et al. (1999). "CCG repeats in cDNAs from human brain". Hum. Genet. 103 (6): 666–73. PMID 9921901.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Okamoto N, Fujikawa-Adachi K, Nishimori I; et al. (2001). "cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain". Biochim. Biophys. Acta. 1518 (3): 311–6. PMID 11311946.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Taniuchi K, Nishimori I, Takeuchi T; et al. (2002). "Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain". Neuroscience. 112 (1): 93–9. PMID 12044474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)