Adamantinoma

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Overview

Adamantinoma is a rare bone cancer, making up less than 1% of all bone cancers. It predominantly arises in bone in a subcutaneous location (85% are in the tibia). Most commonly, patients are in their second or third decade, but it can occur over a wide age range.

Histologically, islands of epithelial cells are found in a fibrous stroma.

Treatment consists of wide resection or amputation. Metastases are rare at presentation but may occur in up to 30% of patients during the disease course. Prognosis is excellent, with overall survival of 85% at 10 years, but is lower when wide surgical margins cannot be obtained.

References

• Campbell's Operative Orthopedics (10th edition ed.). 2003.CS1 maint: Extra text (link)

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