Squamous cell carcinoma of the skin risk factors

Squamous cell carcinoma of the skin Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2], Raviteja Guddeti, M.B.B.S. [3]

Risk Factors

Smoking is a significant risk factor. Other risk factors include sun exposure, radiation therapy, exposure to carcinogens, chronic skin irritation or inflammation, genetic diseases, and presence of premalignant lesions. Squamous cell cancer can also occur after organ (e.g. heart, kidney) transplantation. Anti-rejection drugs, that ensure the organ is not rejected by the body, can also suppress the immune system. This can be a major factor towards squamous cell skin cancer.