Cardiac tamponade natural history, complications and prognosis

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Overview

Cardiac tamponade is a life-threatening condition requiring urgent intervention to remove the pericardial fluid. Complications include pulmonary edema, cardiac failure, cardiogenic shock and ultimately death.

Cardiac tamponade has a good prognosis if detected early and treated immediately. Short-term survival is mostly dependent on early diagnosis and relief of tamponade. Long-term survival depends upon the prognosis of the underlying cause, irrespective of the mode of treatment[1].

Natural History and Complications

Cardiac tamponade is a life-threatening condition requiring urgent intervention to remove the fluid from the pericardial cavity. If untreated, patient may develop following complications:

  • Pulmonary edema due to decreased forward flow of blood from left ventricle and increased pressures within the pulmonary vasculature.
  • Cardiac failure secondary to inadequate ventricular filling and cardiac output.
  • Cardiogenic shock
  • Death

Prognosis

  • Prognosis is good with early recognition and management of the condition and the underlying cause of the tamponade. 3.2% of total deaths, over a 10-year period, were attributable to cardiac tamponade in a postmortem study of 14,368 patients in County of Cornwall, UK between 1995 and 2004[2] and was mostly attributed to rupture of an acute myocardial infarction or intrapericardial rupture of a dissecting ascending aortic aneurysm.
  • Cardiac tamponade caused by central venous catheters had a mortality rate of 77% before 1980 and 47% between 1980-1989[3].
  • Patients with underlying malignancy has the highest rate of mortality[4]. Short-term survival is mostly dependent on early diagnosis and relief of tamponade. Long-term survival depends upon the prognosis of the underlying cause, irrespective of the mode of treatment[1].
  • Tamponade secondary to idiopathic effusion and penetrating chest wounds, has been shown to be associated with better outcomes with emergent removal of pericardial fluid.

References

  1. 1.0 1.1 Markiewicz W, Borovik R, Ecker S (1986). "Cardiac tamponade in medical patients: treatment and prognosis in the echocardiographic era". Am Heart J. 111 (6): 1138–42. PMID 3716989.
  2. Swaminathan A, Kandaswamy K, Powari M, Mathew J (2007). "Dying from cardiac tamponade". World J Emerg Surg. 2: 22. doi:10.1186/1749-7922-2-22. PMC 2042492. PMID 17822563.
  3. Nasim A, Cooper GG, Ah-See AK (1992). "Cardiac tamponade due to central venous catheterization". J R Coll Surg Edinb. 37 (5): 337–9. PMID 1282555.
  4. Soler-Soler J, Sagristà-Sauleda J, Permanyer-Miralda G (2001). "Management of pericardial effusion". Heart. 86 (2): 235–40. PMC 1729838. PMID 11454853.

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