Renal agenesis overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Renal agenesis is the absence of one (unilateral) or both (bilateral) kidneys at birth. Renal agenesis is a medical condition in which one (unilateral) or both (bilateral) fetal kidneys fail to develop.

It can be associated with RET or UPK3A.[1]


Epidemiology and Demographics

The general incidence of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals. The incidence of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies. Males are more commonly affected by unilateral renal agenesis (URA) than females. The mortality rate of bilateral renal agenesis (BRA) without prenatal therapy is 100%.

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